Browse anti-prokaryotic immune system families by CLAN ID

AD families AD genes Defense system CLAN ID Phages/MGEs References Description
APIS107 dam restriction-modification (RM) CLAN026 Escherichia phage T4 PMID:6307815 DNA adenine methylases methylate adenine residues in specific sequences, the methylation site of the host Escherichia coli dam+ methylase. Methylation protects the site against cleavage by the MboI restriction nuclease.
APIS152 dmt restriction-modification (RM) CLAN026 Escherichia phage P1 PMID:14715260 DNA methyltransferase (M.EcoP1I) encoded by prophage P1, may protect the phage genome from restriction by type III restriction enzymes and thus could be considered as an anti-restriction system.
APIS161 CLAN026
APIS192 CLAN026