CAZyme3D

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Entry ID

Information for CAZyme ID: QPC82847.1

Basic Information

GenBank IDQPC82847.1
FamilyGH99
Sequence Length400
UniProt IDA0A7S8E9J6(100,100)Download
Average pLDDT?88.70
CAZy50 ID98953
CAZy50 RepYes, QPC82847.1
Structure ClusterSC_GH99_clus18
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID2710758
KingdomBacteria
PhylumChloroflexota
ClassCandidatus Thermofonsia
OrderPhototrophicales
FamilyPhototrophicaceae
GenusPhototrophicus
SpeciesPhototrophicus methaneseepsis

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MKQFFVVLIT  VMSLMVAGFT  PSQAQSEQHV  WAFYMGFWAG  GASWDWQADV  LTDYPAIGNY60
DSRDGGVAGT  QIDQAKSAGI  DGFVVSWNGL  GDQGTSTPVL  NNLLDRAGER  GFQVGAAIDA120
FTPEFVSNRD  TLISSISWLV  NDRANHPAYL  RYQGKPVIFF  AFQGNLGLSS  AEWQEIRNSI180
DPDRNTYWIA  EGLNGCCLYG  GAMDGMYAFN  LAWANGSSGT  YSGQRSRVLN  AGGSIYIPTV240
HPGWDEALIA  ARDGRPNPTS  PRGRQDGQFL  ANSFRGAAAS  GADIILVGTW  NEYMENSHIE300
PSQQYGTQSL  DVLRPLIEEW  RSTGGTSAPA  EEAAPDIEGP  AVQANSRLNV  RYGPGTDYDV360
MGAISPGRWY  ALIREENGWY  VISYNGQEGY  VSGDYVQVRQ  400

Predicted 3D structure by AlphaFold2 with pLDDT = 88.70 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MKQFFVVLIT  VMSLMVAGFT  PSQAQSEQHV  WAFYMGFWAG  GASWDWQADV  LTDYPAIGNY60
DSRDGGVAGT  QIDQAKSAGI  DGFVVSWNGL  GDQGTSTPVL  NNLLDRAGER  GFQVGAAIDA120
FTPEFVSNRD  TLISSISWLV  NDRANHPAYL  RYQGKPVIFF  AFQGNLGLSS  AEWQEIRNSI180
DPDRNTYWIA  EGLNGCCLYG  GAMDGMYAFN  LAWANGSSGT  YSGQRSRVLN  AGGSIYIPTV240
HPGWDEALIA  ARDGRPNPTS  PRGRQDGQFL  ANSFRGAAAS  GADIILVGTW  NEYMENSHIE300
PSQQYGTQSL  DVLRPLIEEW  RSTGGTSAPA  EEAAPDIEGP  AVQANSRLNV  RYGPGTDYDV360
MGAISPGRWY  ALIREENGWY  VISYNGQEGY  VSGDYVQVRQ  400

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GH99(54-305)

MKQFFVVLIT  VMSLMVAGFT  PSQAQSEQHV  WAFYMGFWAG  GASWDWQADV  LTDYPAIGNY60
DSRDGGVAGT  QIDQAKSAGI  DGFVVSWNGL  GDQGTSTPVL  NNLLDRAGER  GFQVGAAIDA120
FTPEFVSNRD  TLISSISWLV  NDRANHPAYL  RYQGKPVIFF  AFQGNLGLSS  AEWQEIRNSI180
DPDRNTYWIA  EGLNGCCLYG  GAMDGMYAFN  LAWANGSSGT  YSGQRSRVLN  AGGSIYIPTV240
HPGWDEALIA  ARDGRPNPTS  PRGRQDGQFL  ANSFRGAAAS  GADIILVGTW  NEYMENSHIE300
PSQQYGTQSL  DVLRPLIEEW  RSTGGTSAPA  EEAAPDIEGP  AVQANSRLNV  RYGPGTDYDV360
MGAISPGRWY  ALIREENGWY  VISYNGQEGY  VSGDYVQVRQ  400

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help