CAZyme3D

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Entry ID

Information for CAZyme ID: QFG03146.1

Basic Information

GenBank IDQFG03146.1
FamilyCBM50, GH23
Sequence Length291
UniProt IDA0A5J6SYL2(100,100)Download
Average pLDDT?65.76
CAZy50 ID159562
CAZy50 RepYes, QFG03146.1
Structure ClusterSC_CBM50_clus26, SC_CBM50_clus8, SC_GH23_clus534
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID2601677
KingdomBacteria
PhylumChloroflexota
ClassTepidiformia
OrderTepidiformales
FamilyTepidiformaceae
GenusTepidiforma
SpeciesTepidiforma bonchosmolovskayae

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MLPHTPPAAA  NRAPFLRRIL  LAMLAAAAAA  PLAVASARTH  EVQPGETLSA  IALRYGVDVD60
ALAAANGIAN  PDLIFAGQLL  TIAESSPAVP  PPGGAVAPPA  ARSYVVEPGD  TLSSIALAHG120
TTVHAVAEAN  GIDDHDRIFA  GQLLVIPAPT  RAPADPAVSR  PAIEALLRAA  AAEYGIPPSV180
LLGLAWLESG  WNQAMVSPAG  AVGIMQLMPA  TAEWGLEYLA  PGAVNWRTEP  ADNIRLGAAV240
FAHMLWQAGG  DLKIALAFYY  QGWWSIEQFG  IFDETLQYVA  NVLAIASGFD  D291

Predicted 3D structure by AlphaFold2 with pLDDT = 65.76 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MLPHTPPAAA  NRAPFLRRIL  LAMLAAAAAA  PLAVASARTH  EVQPGETLSA  IALRYGVDVD60
ALAAANGIAN  PDLIFAGQLL  TIAESSPAVP  PPGGAVAPPA  ARSYVVEPGD  TLSSIALAHG120
TTVHAVAEAN  GIDDHDRIFA  GQLLVIPAPT  RAPADPAVSR  PAIEALLRAA  AAEYGIPPSV180
LLGLAWLESG  WNQAMVSPAG  AVGIMQLMPA  TAEWGLEYLA  PGAVNWRTEP  ADNIRLGAAV240
FAHMLWQAGG  DLKIALAFYY  QGWWSIEQFG  IFDETLQYVA  NVLAIASGFD  D291

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : CBM50(40-82)+CBM50(104-147)+GH23(177-287)

MLPHTPPAAA  NRAPFLRRIL  LAMLAAAAAA  PLAVASARTH  EVQPGETLSA  IALRYGVDVD60
ALAAANGIAN  PDLIFAGQLL  TIAESSPAVP  PPGGAVAPPA  ARSYVVEPGD  TLSSIALAHG120
TTVHAVAEAN  GIDDHDRIFA  GQLLVIPAPT  RAPADPAVSR  PAIEALLRAA  AAEYGIPPSV180
LLGLAWLESG  WNQAMVSPAG  AVGIMQLMPA  TAEWGLEYLA  PGAVNWRTEP  ADNIRLGAAV240
FAHMLWQAGG  DLKIALAFYY  QGWWSIEQFG  IFDETLQYVA  NVLAIASGFD  D291

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help