CAZyme3D

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Entry ID

Information for CAZyme ID: QER66589.1

Basic Information

GenBank IDQER66589.1
FamilyCE4
Sequence Length276
UniProt IDA0A5P1X1P1(100,100)Download
Average pLDDT?84.89
CAZy50 ID164344
CAZy50 RepYes, QER66589.1
Structure ClusterSC_CE4_clus45
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID1296540
KingdomBacteria
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyLactobacillaceae
GenusPaucilactobacillus
SpeciesPaucilactobacillus nenjiangensis

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MEYIGTMKKS  RILIGLISIV  IILFGVVTFA  SHAHSEKLSA  ESSARSKMSS  KKIASSRVSS60
SSSSAKVASE  KANDSIIYLT  FDDGPQESTT  PQLLKILKKE  QVHATFFVTG  HGPDSLIKQE120
YEQGNVIGLH  TMTHDYATVY  ASPAAYFNDL  QQISDRVYRL  TGERSMMVRV  PGGSANQVSH180
GLMPQILPQL  VQKGYKYFDW  NISSGDGGYE  ATAEEPYQHV  TTTLVPHSKN  VVLMHDTKQT240
SIDAVQRIIE  FGKANGYKFE  TLNMNSWAPQ  QISMPQ276

Predicted 3D structure by AlphaFold2 with pLDDT = 84.89 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MEYIGTMKKS  RILIGLISIV  IILFGVVTFA  SHAHSEKLSA  ESSARSKMSS  KKIASSRVSS60
SSSSAKVASE  KANDSIIYLT  FDDGPQESTT  PQLLKILKKE  QVHATFFVTG  HGPDSLIKQE120
YEQGNVIGLH  TMTHDYATVY  ASPAAYFNDL  QQISDRVYRL  TGERSMMVRV  PGGSANQVSH180
GLMPQILPQL  VQKGYKYFDW  NISSGDGGYE  ATAEEPYQHV  TTTLVPHSKN  VVLMHDTKQT240
SIDAVQRIIE  FGKANGYKFE  TLNMNSWAPQ  QISMPQ276

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : CE4(71-187)

MEYIGTMKKS  RILIGLISIV  IILFGVVTFA  SHAHSEKLSA  ESSARSKMSS  KKIASSRVSS60
SSSSAKVASE  KANDSIIYLT  FDDGPQESTT  PQLLKILKKE  QVHATFFVTG  HGPDSLIKQE120
YEQGNVIGLH  TMTHDYATVY  ASPAAYFNDL  QQISDRVYRL  TGERSMMVRV  PGGSANQVSH180
GLMPQILPQL  VQKGYKYFDW  NISSGDGGYE  ATAEEPYQHV  TTTLVPHSKN  VVLMHDTKQT240
SIDAVQRIIE  FGKANGYKFE  TLNMNSWAPQ  QISMPQ276

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help