CAZyme3D

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Entry ID

Information for CAZyme ID: QEH36390.1

Basic Information

GenBank IDQEH36390.1
FamilyGT2
Sequence Length320
UniProt IDA0A5B9W941(100,100)Download
Average pLDDT?91.14
CAZy50 ID147030
CAZy50 RepYes, QEH36390.1
Structure ClusterSC_GT2_clus508
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID406548
KingdomBacteria
PhylumPlanctomycetota
ClassPlanctomycetia
OrderIsosphaerales
FamilyIsosphaeraceae
GenusAquisphaera
SpeciesAquisphaera giovannonii

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MSVLMPVYNT  RRYVRQAVES  ILGQTFEDFE  LIVMDDQSTD  GSLGVVEECR  RRDDRVRLFP60
RAKTGYCRLL  NEALGLARGR  YLARMDSDDV  SLPDRFEKQV  AYLEANSDCV  AVGCRVREID120
PHGLHLDVSR  NELDHDGIVA  RLLEGAGAEI  PHPGVMMRTS  AVVEAGGYRP  EFEPVEDLDL180
YLRLAERGRL  ANLPGVLLEY  RQHFTSVNYL  RADEQVRLAS  LVVAEAMTRR  GQAVPGSFAV240
PPWRMPTKAE  SYRNWAEAAL  RSRRRGVAME  YAVKGVMAGP  AEGVSWVVLA  GVLAGTLRSF300
ARSARDAFRR  MASSPGGSGR  320

Predicted 3D structure by AlphaFold2 with pLDDT = 91.14 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MSVLMPVYNT  RRYVRQAVES  ILGQTFEDFE  LIVMDDQSTD  GSLGVVEECR  RRDDRVRLFP60
RAKTGYCRLL  NEALGLARGR  YLARMDSDDV  SLPDRFEKQV  AYLEANSDCV  AVGCRVREID120
PHGLHLDVSR  NELDHDGIVA  RLLEGAGAEI  PHPGVMMRTS  AVVEAGGYRP  EFEPVEDLDL180
YLRLAERGRL  ANLPGVLLEY  RQHFTSVNYL  RADEQVRLAS  LVVAEAMTRR  GQAVPGSFAV240
PPWRMPTKAE  SYRNWAEAAL  RSRRRGVAME  YAVKGVMAGP  AEGVSWVVLA  GVLAGTLRSF300
ARSARDAFRR  MASSPGGSGR  320

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT2(2-158)

MSVLMPVYNT  RRYVRQAVES  ILGQTFEDFE  LIVMDDQSTD  GSLGVVEECR  RRDDRVRLFP60
RAKTGYCRLL  NEALGLARGR  YLARMDSDDV  SLPDRFEKQV  AYLEANSDCV  AVGCRVREID120
PHGLHLDVSR  NELDHDGIVA  RLLEGAGAEI  PHPGVMMRTS  AVVEAGGYRP  EFEPVEDLDL180
YLRLAERGRL  ANLPGVLLEY  RQHFTSVNYL  RADEQVRLAS  LVVAEAMTRR  GQAVPGSFAV240
PPWRMPTKAE  SYRNWAEAAL  RSRRRGVAME  YAVKGVMAGP  AEGVSWVVLA  GVLAGTLRSF300
ARSARDAFRR  MASSPGGSGR  320

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help