CAZyme3D

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Entry ID

Information for CAZyme ID: QDM43599.1

Basic Information

GenBank IDQDM43599.1
FamilyCE4
Sequence Length297
UniProt IDA0A378ZJZ4(100,100)Download
Average pLDDT?81.13
CAZy50 ID157198
CAZy50 RepYes, QDM43599.1
Structure ClusterSC_CE4_clus32
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID49283
KingdomBacteria
PhylumBacillota
ClassBacilli
OrderBacillales
FamilyPaenibacillaceae
GenusPaenibacillus
SpeciesPaenibacillus thiaminolyticus

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MKRVRKRLER  AARIGTICLV  AIALLFVAPE  TSVHKGKAAG  KVAGDEAVQQ  RHPAAVAMEE60
LKPMPANAAV  KPVRKDRAYF  EERGDIVWEV  PSAGKRIALT  FDDGPDPKNT  PAILELLKQH120
DAKATFFLVG  WRVKDNPELV  KRTVREGHEV  GNHSYYHKYF  RRGISAAEIK  EDMMKAHRVI180
KEVTGTAPHL  YRPPGGYYNQ  QLVDVAHAND  YRIVMWSWHQ  DTKDWSSPGV  QRIVNKVLNS240
ARNGDIVLMH  DFAEGRAQTV  EALKTILPEL  KKRGYSLVTV  SELMSHRVKG  ELKTPRK297

Predicted 3D structure by AlphaFold2 with pLDDT = 81.13 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MKRVRKRLER  AARIGTICLV  AIALLFVAPE  TSVHKGKAAG  KVAGDEAVQQ  RHPAAVAMEE60
LKPMPANAAV  KPVRKDRAYF  EERGDIVWEV  PSAGKRIALT  FDDGPDPKNT  PAILELLKQH120
DAKATFFLVG  WRVKDNPELV  KRTVREGHEV  GNHSYYHKYF  RRGISAAEIK  EDMMKAHRVI180
KEVTGTAPHL  YRPPGGYYNQ  QLVDVAHAND  YRIVMWSWHQ  DTKDWSSPGV  QRIVNKVLNS240
ARNGDIVLMH  DFAEGRAQTV  EALKTILPEL  KKRGYSLVTV  SELMSHRVKG  ELKTPRK297

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : CE4(92-214)

MKRVRKRLER  AARIGTICLV  AIALLFVAPE  TSVHKGKAAG  KVAGDEAVQQ  RHPAAVAMEE60
LKPMPANAAV  KPVRKDRAYF  EERGDIVWEV  PSAGKRIALT  FDDGPDPKNT  PAILELLKQH120
DAKATFFLVG  WRVKDNPELV  KRTVREGHEV  GNHSYYHKYF  RRGISAAEIK  EDMMKAHRVI180
KEVTGTAPHL  YRPPGGYYNQ  QLVDVAHAND  YRIVMWSWHQ  DTKDWSSPGV  QRIVNKVLNS240
ARNGDIVLMH  DFAEGRAQTV  EALKTILPEL  KKRGYSLVTV  SELMSHRVKG  ELKTPRK297

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help