CAZyme3D

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Entry ID

Information for CAZyme ID: QCO71589.1

Basic Information

GenBank IDQCO71589.1
FamilyGT2
Sequence Length277
UniProt IDQCO71589.1(MOD)Download
Average pLDDT?94.50
CAZy50 ID164175
CAZy50 RepYes, QCO71589.1
Structure ClusterSC_GT2_clus738
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID1307
KingdomBacteria
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus suis

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MITNNFSVLM  SVYAKENPKY  LSDALDSIFQ  QNLLANEVVI  VKDGPLTDEL  DSVIETYEKR60
YSELKVVAIP  ENKGLGLALN  EGLKHCSYDW  VARMDSDDVA  LKNRFQVQVD  FINSHPEIDL120
VGSDIQEFSN  EIDEIVSYKK  MPTEHFQISE  MLKQRTPVCH  MTVFFRKQAV  IEAGNYLDLP180
YVEDYYLWSR  MIINGSRFAN  IPKALVLVRV  GNGMAKRRGN  RKSISSWKTV  QQFLLKNNVI240
NRIEYIKNMI  IIRIFIYTPA  SVKELLYKYI  LRSGVTN277

Predicted 3D structure by AlphaFold2 with pLDDT = 94.50 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MITNNFSVLM  SVYAKENPKY  LSDALDSIFQ  QNLLANEVVI  VKDGPLTDEL  DSVIETYEKR60
YSELKVVAIP  ENKGLGLALN  EGLKHCSYDW  VARMDSDDVA  LKNRFQVQVD  FINSHPEIDL120
VGSDIQEFSN  EIDEIVSYKK  MPTEHFQISE  MLKQRTPVCH  MTVFFRKQAV  IEAGNYLDLP180
YVEDYYLWSR  MIINGSRFAN  IPKALVLVRV  GNGMAKRRGN  RKSISSWKTV  QQFLLKNNVI240
NRIEYIKNMI  IIRIFIYTPA  SVKELLYKYI  LRSGVTN277

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT2(7-160)

MITNNFSVLM  SVYAKENPKY  LSDALDSIFQ  QNLLANEVVI  VKDGPLTDEL  DSVIETYEKR60
YSELKVVAIP  ENKGLGLALN  EGLKHCSYDW  VARMDSDDVA  LKNRFQVQVD  FINSHPEIDL120
VGSDIQEFSN  EIDEIVSYKK  MPTEHFQISE  MLKQRTPVCH  MTVFFRKQAV  IEAGNYLDLP180
YVEDYYLWSR  MIINGSRFAN  IPKALVLVRV  GNGMAKRRGN  RKSISSWKTV  QQFLLKNNVI240
NRIEYIKNMI  IIRIFIYTPA  SVKELLYKYI  LRSGVTN277

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help