CAZyme3D

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Entry ID

Information for CAZyme ID: NP_849210.1

Basic Information

GenBank IDNP_849210.1
FamilyGT31
Sequence Length399
UniProt IDQ8VI16(100,100)Download
Average pLDDT?81.68
CAZy50 ID99189
CAZy50 RepYes, NP_849210.1
Structure ClusterSC_GT31_clus6
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID10090
KingdomEukaryota
PhylumChordata
ClassMammalia
OrderRodentia
FamilyMuridae
GenusMus
SpeciesMus musculus

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MRRRRRPRLC  PDAWLTLLLS  AALGLLLYAQ  RDVASPTTRP  PARGPQLPRP  TPSLRARELP60
NTARAAPLAY  EGDTPVPPTP  TDPFDFGGYL  RAKDQRRFPL  LINQRRKCRS  DGASGGSPDL120
LIAVKSVAAD  FERREAVRQT  WGAEGRVQGA  LVRRVFLLGV  PKGAGSGGAG  TRSHWRTLLE180
AESRAYADIL  LWAFEDTFFN  LTLKEIHFLS  WASAFCPDVH  FVFKGDADVF  VHVRNLLQFL240
ELRDPAQDLL  AGDVIVQARP  IRARASKYFI  PRAVYGLPVY  PAYAGGGGFV  LSGATLRRLA300
DACSQVELFP  IDDVFLGMCL  QRLRLTPEPH  PAFRTFGISQ  PSAAPHLRTF  DPCFYRELVV360
VHGLSAADIW  LMWRLLHGPQ  GPVCAHPQPV  ATGPFQWNS399

Predicted 3D structure by AlphaFold2 with pLDDT = 81.68 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MRRRRRPRLC  PDAWLTLLLS  AALGLLLYAQ  RDVASPTTRP  PARGPQLPRP  TPSLRARELP60
NTARAAPLAY  EGDTPVPPTP  TDPFDFGGYL  RAKDQRRFPL  LINQRRKCRS  DGASGGSPDL120
LIAVKSVAAD  FERREAVRQT  WGAEGRVQGA  LVRRVFLLGV  PKGAGSGGAG  TRSHWRTLLE180
AESRAYADIL  LWAFEDTFFN  LTLKEIHFLS  WASAFCPDVH  FVFKGDADVF  VHVRNLLQFL240
ELRDPAQDLL  AGDVIVQARP  IRARASKYFI  PRAVYGLPVY  PAYAGGGGFV  LSGATLRRLA300
DACSQVELFP  IDDVFLGMCL  QRLRLTPEPH  PAFRTFGISQ  PSAAPHLRTF  DPCFYRELVV360
VHGLSAADIW  LMWRLLHGPQ  GPVCAHPQPV  ATGPFQWNS399

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT31(132-328)

MRRRRRPRLC  PDAWLTLLLS  AALGLLLYAQ  RDVASPTTRP  PARGPQLPRP  TPSLRARELP60
NTARAAPLAY  EGDTPVPPTP  TDPFDFGGYL  RAKDQRRFPL  LINQRRKCRS  DGASGGSPDL120
LIAVKSVAAD  FERREAVRQT  WGAEGRVQGA  LVRRVFLLGV  PKGAGSGGAG  TRSHWRTLLE180
AESRAYADIL  LWAFEDTFFN  LTLKEIHFLS  WASAFCPDVH  FVFKGDADVF  VHVRNLLQFL240
ELRDPAQDLL  AGDVIVQARP  IRARASKYFI  PRAVYGLPVY  PAYAGGGGFV  LSGATLRRLA300
DACSQVELFP  IDDVFLGMCL  QRLRLTPEPH  PAFRTFGISQ  PSAAPHLRTF  DPCFYRELVV360
VHGLSAADIW  LMWRLLHGPQ  GPVCAHPQPV  ATGPFQWNS399

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help

qseqidqlensseqidpidentevaluelengthqstartqendqcovhspscovhsp
NP_849210.1399NP_849210.11001.55e-3063991399100100