CAZyme3D

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Entry ID

Information for CAZyme ID: CAO81410.1

Basic Information

GenBank IDCAO81410.1
FamilyGT4
Sequence Length390
UniProt IDB0VFW8(100,100)Download
Average pLDDT?89.91
CAZy50 ID104909
CAZy50 RepYes, CAO81410.1
Structure ClusterSC_GT4_clus864
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID459349
KingdomBacteria
PhylumCandidatus Cloacimonadota
ClassCandidatus Cloacimonadia
OrderCandidatus Cloacimonadales
FamilyCandidatus Cloacimonadaceae
GenusCandidatus Cloacimonas
SpeciesCandidatus Cloacimonas acidaminovorans

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MPISKRKLLL  ITDLYPNKFN  PVNGVFVQQQ  AIELSRYYQV  QVVAACDKNP  YLVYEHHQDG60
FPVKLICYPY  WQKYFLTSLI  TYRILALPAI  KRCYKRFQPD  LIHIHDYRHI  PELFWLKPWL120
NKLSVPKYLT  LHNIRTHPER  LKNNPRIGFY  RWALKKTLTG  WDHIFTVNSK  IAKWVKQYNP180
ASKVTIIGNA  ISEFADVGPQ  LIEPYKNILL  ADYFHLISIG  NLFTEKGFSY  LIEAIYLLKK240
EGLQVQLIIA  GDGDRRKELE  NQVKTKNLNE  EVIFLGRIEN  TLLRNILPLF  DLFVLASYSE300
TFGIVFLEAM  FAGLPVIGIK  EEGIYGLAED  GKQALFAEPK  NSKDLAAKIK  LLMMKPLLRE360
EIAKAGQRLV  QEKYMLKELI  KRIIAVYEQK  390

Predicted 3D structure by AlphaFold2 with pLDDT = 89.91 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MPISKRKLLL  ITDLYPNKFN  PVNGVFVQQQ  AIELSRYYQV  QVVAACDKNP  YLVYEHHQDG60
FPVKLICYPY  WQKYFLTSLI  TYRILALPAI  KRCYKRFQPD  LIHIHDYRHI  PELFWLKPWL120
NKLSVPKYLT  LHNIRTHPER  LKNNPRIGFY  RWALKKTLTG  WDHIFTVNSK  IAKWVKQYNP180
ASKVTIIGNA  ISEFADVGPQ  LIEPYKNILL  ADYFHLISIG  NLFTEKGFSY  LIEAIYLLKK240
EGLQVQLIIA  GDGDRRKELE  NQVKTKNLNE  EVIFLGRIEN  TLLRNILPLF  DLFVLASYSE300
TFGIVFLEAM  FAGLPVIGIK  EEGIYGLAED  GKQALFAEPK  NSKDLAAKIK  LLMMKPLLRE360
EIAKAGQRLV  QEKYMLKELI  KRIIAVYEQK  390

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT4(216-362)

MPISKRKLLL  ITDLYPNKFN  PVNGVFVQQQ  AIELSRYYQV  QVVAACDKNP  YLVYEHHQDG60
FPVKLICYPY  WQKYFLTSLI  TYRILALPAI  KRCYKRFQPD  LIHIHDYRHI  PELFWLKPWL120
NKLSVPKYLT  LHNIRTHPER  LKNNPRIGFY  RWALKKTLTG  WDHIFTVNSK  IAKWVKQYNP180
ASKVTIIGNA  ISEFADVGPQ  LIEPYKNILL  ADYFHLISIG  NLFTEKGFSY  LIEAIYLLKK240
EGLQVQLIIA  GDGDRRKELE  NQVKTKNLNE  EVIFLGRIEN  TLLRNILPLF  DLFVLASYSE300
TFGIVFLEAM  FAGLPVIGIK  EEGIYGLAED  GKQALFAEPK  NSKDLAAKIK  LLMMKPLLRE360
EIAKAGQRLV  QEKYMLKELI  KRIIAVYEQK  390

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help