CAZyme3D

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Entry ID

Information for CAZyme ID: CAD7244344.1

Basic Information

GenBank IDCAD7244344.1
FamilyGH9
Sequence Length444
UniProt IDA0A7R8X7I6(100,100)Download
Average pLDDT?84.19
CAZy50 ID81551
CAZy50 RepYes, CAD7244344.1
Structure ClusterSC_GH9_clus26
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID69355
KingdomEukaryota
PhylumArthropoda
ClassOstracoda
OrderPodocopida
FamilyDarwinulidae
GenusDarwinula
SpeciesDarwinula stevensoni

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MRCFGSPEFR  SPSVVRPPAG  SPHPRQTLHD  HEIRISRLPN  LLLLLLAFLG  MSQVKGDYDY60
ASAIRLSYKF  YEAQRAGQLP  DNHIPWRKSS  FLNDGRDKGI  NLVGGYFDAG  DYVKFGFPMA120
YTTTVLAWGM  VEYANAYNKA  GLAAAGRAQL  RWATDYFIKA  HPSAKKLFGQ  VGKGDVDHSY180
WGRPEDWPSN  MERPSYFIDE  DSPGSDLAAE  TAAAMAASSM  VFRGNDDTYA  NTLLRHAREL240
YAFADENRGL  YSDSITDAQE  FYPSSAYEDE  LAWAAAWLYR  ATRETSYLND  AERKYVEFGL300
DDRPSEFSWD  DKNAGVQVLL  AVLTGKTKYK  TAVKTFCDYM  VNEVPRTPKG  LVFIQKWGVL360
RHAANVAYVC  LVFDVHTSKV  VILYDMYFFL  VFFCSSCPTV  QACGGCQCSW  SYFYSPNPNP420
NLLEGALVGG  PDKQDRFKDD  RHLM444

Predicted 3D structure by AlphaFold2 with pLDDT = 84.19 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MRCFGSPEFR  SPSVVRPPAG  SPHPRQTLHD  HEIRISRLPN  LLLLLLAFLG  MSQVKGDYDY60
ASAIRLSYKF  YEAQRAGQLP  DNHIPWRKSS  FLNDGRDKGI  NLVGGYFDAG  DYVKFGFPMA120
YTTTVLAWGM  VEYANAYNKA  GLAAAGRAQL  RWATDYFIKA  HPSAKKLFGQ  VGKGDVDHSY180
WGRPEDWPSN  MERPSYFIDE  DSPGSDLAAE  TAAAMAASSM  VFRGNDDTYA  NTLLRHAREL240
YAFADENRGL  YSDSITDAQE  FYPSSAYEDE  LAWAAAWLYR  ATRETSYLND  AERKYVEFGL300
DDRPSEFSWD  DKNAGVQVLL  AVLTGKTKYK  TAVKTFCDYM  VNEVPRTPKG  LVFIQKWGVL360
RHAANVAYVC  LVFDVHTSKV  VILYDMYFFL  VFFCSSCPTV  QACGGCQCSW  SYFYSPNPNP420
NLLEGALVGG  PDKQDRFKDD  RHLM444

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GH9(59-376)

MRCFGSPEFR  SPSVVRPPAG  SPHPRQTLHD  HEIRISRLPN  LLLLLLAFLG  MSQVKGDYDY60
ASAIRLSYKF  YEAQRAGQLP  DNHIPWRKSS  FLNDGRDKGI  NLVGGYFDAG  DYVKFGFPMA120
YTTTVLAWGM  VEYANAYNKA  GLAAAGRAQL  RWATDYFIKA  HPSAKKLFGQ  VGKGDVDHSY180
WGRPEDWPSN  MERPSYFIDE  DSPGSDLAAE  TAAAMAASSM  VFRGNDDTYA  NTLLRHAREL240
YAFADENRGL  YSDSITDAQE  FYPSSAYEDE  LAWAAAWLYR  ATRETSYLND  AERKYVEFGL300
DDRPSEFSWD  DKNAGVQVLL  AVLTGKTKYK  TAVKTFCDYM  VNEVPRTPKG  LVFIQKWGVL360
RHAANVAYVC  LVFDVHTSKV  VILYDMYFFL  VFFCSSCPTV  QACGGCQCSW  SYFYSPNPNP420
NLLEGALVGG  PDKQDRFKDD  RHLM444

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help