CAZyme3D

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Entry ID

Information for CAZyme ID: BBH91417.1

Basic Information

GenBank IDBBH91417.1
FamilyCE4
Sequence Length300
UniProt IDA0A455SST1(100,100)Download
Average pLDDT?79.14
CAZy50 ID156020
CAZy50 RepYes, BBH91417.1
Structure ClusterSC_CE4_clus148
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID2490863
KingdomBacteria
PhylumChloroflexota
ClassKtedonobacteria
OrderKtedonobacterales
FamilyThermosporotrichaceae
GenusThermosporothrix
SpeciesThermosporothrix sp. COM3

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MSAHGRDNNH  KPSFRFNKKL  HLPIILLAIL  SASLWAVGSF  AAGIAAAEDE  KNRALTITPT60
PGPSPTIVFT  PTPTPTIEPT  PSPTITGDST  PIGNPGNIPN  VITNGSRNRL  EIALTFDDGP120
HPQYTPQVLQ  ILKRYNIKAT  FFCLGQMIQE  NPDLVRQEHQ  AGHVVASHSW  SHPDLTTLSM180
DQLQKELKNT  SDLIYNTIGE  RPTLVRPPYG  SYNNNVVQVA  NSLSEKIIIW  DVDTNDWQRK240
GVDSIVNTAF  QEAGKGSIIL  MHDAGGERSQ  TIAALPRIIE  GLKARGYSFV  TVPELLSHMG300
300

Predicted 3D structure by AlphaFold2 with pLDDT = 79.14 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MSAHGRDNNH  KPSFRFNKKL  HLPIILLAIL  SASLWAVGSF  AAGIAAAEDE  KNRALTITPT60
PGPSPTIVFT  PTPTPTIEPT  PSPTITGDST  PIGNPGNIPN  VITNGSRNRL  EIALTFDDGP120
HPQYTPQVLQ  ILKRYNIKAT  FFCLGQMIQE  NPDLVRQEHQ  AGHVVASHSW  SHPDLTTLSM180
DQLQKELKNT  SDLIYNTIGE  RPTLVRPPYG  SYNNNVVQVA  NSLSEKIIIW  DVDTNDWQRK240
GVDSIVNTAF  QEAGKGSIIL  MHDAGGERSQ  TIAALPRIIE  GLKARGYSFV  TVPELLSHMG300
300

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : CE4(107-223)

MSAHGRDNNH  KPSFRFNKKL  HLPIILLAIL  SASLWAVGSF  AAGIAAAEDE  KNRALTITPT60
PGPSPTIVFT  PTPTPTIEPT  PSPTITGDST  PIGNPGNIPN  VITNGSRNRL  EIALTFDDGP120
HPQYTPQVLQ  ILKRYNIKAT  FFCLGQMIQE  NPDLVRQEHQ  AGHVVASHSW  SHPDLTTLSM180
DQLQKELKNT  SDLIYNTIGE  RPTLVRPPYG  SYNNNVVQVA  NSLSEKIIIW  DVDTNDWQRK240
GVDSIVNTAF  QEAGKGSIIL  MHDAGGERSQ  TIAALPRIIE  GLKARGYSFV  TVPELLSHMG300
300

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help