CAZyme3D

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Entry ID

Information for CAZyme ID: AYN69337.1

Basic Information

GenBank IDAYN69337.1
FamilyCE4
Sequence Length262
UniProt IDA0A3G2LAR4(100,100)Download
Average pLDDT?96.82
CAZy50 ID168446
CAZy50 RepYes, AYN69337.1
Structure ClusterSC_CE4_clus45
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID1761453
KingdomBacteria
PhylumBacteroidota
ClassFlavobacteriia
OrderFlavobacteriales
FamilyFlavobacteriaceae
GenusEuzebyella
SpeciesEuzebyella marina

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MLSRLIRRRV  IYPTTVVLLV  ALIVLDSFYA  IGWYWYALIV  IAWFLVTLSG  SFFIQWNFHL60
TSYHSNKKTP  HDWVAITFDD  GPDPEFTPQV  LDLLKKYSAK  ATFFCIGEKI  EAHPSILERI120
IDEGHTIGNH  TFTHSRSFGF  FGVEEVKNEL  QKAKETVQRL  SGRKMDLYRP  AFGVTNPSIE180
KVVEELQLKS  IGWNVRSLDT  TPRSENMVYN  RIVSKVAKGD  IILLHDTSSK  SIAVLERLLV240
FLKDKKLQSV  TVDQLLEIRA  YV262

Predicted 3D structure by AlphaFold2 with pLDDT = 96.82 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MLSRLIRRRV  IYPTTVVLLV  ALIVLDSFYA  IGWYWYALIV  IAWFLVTLSG  SFFIQWNFHL60
TSYHSNKKTP  HDWVAITFDD  GPDPEFTPQV  LDLLKKYSAK  ATFFCIGEKI  EAHPSILERI120
IDEGHTIGNH  TFTHSRSFGF  FGVEEVKNEL  QKAKETVQRL  SGRKMDLYRP  AFGVTNPSIE180
KVVEELQLKS  IGWNVRSLDT  TPRSENMVYN  RIVSKVAKGD  IILLHDTSSK  SIAVLERLLV240
FLKDKKLQSV  TVDQLLEIRA  YV262

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : CE4(67-189)

MLSRLIRRRV  IYPTTVVLLV  ALIVLDSFYA  IGWYWYALIV  IAWFLVTLSG  SFFIQWNFHL60
TSYHSNKKTP  HDWVAITFDD  GPDPEFTPQV  LDLLKKYSAK  ATFFCIGEKI  EAHPSILERI120
IDEGHTIGNH  TFTHSRSFGF  FGVEEVKNEL  QKAKETVQRL  SGRKMDLYRP  AFGVTNPSIE180
KVVEELQLKS  IGWNVRSLDT  TPRSENMVYN  RIVSKVAKGD  IILLHDTSSK  SIAVLERLLV240
FLKDKKLQSV  TVDQLLEIRA  YV262

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help