CAZyme3D

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Entry ID

Information for CAZyme ID: AXA36722.1

Basic Information

GenBank IDAXA36722.1
FamilyGT2
Sequence Length308
UniProt IDA0A2Z4Y7U9(100,100)Download
Average pLDDT?91.22
CAZy50 ID152545
CAZy50 RepYes, AXA36722.1
Structure ClusterSC_GT2_clus911
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID2250252
KingdomBacteria
PhylumCandidatus Sumerlaeota
ClassCandidatus Sumerlaeia
OrderCandidatus Sumerlaeales
FamilyCandidatus Sumerlaeaceae
GenusCandidatus Sumerlaea
SpeciesCandidatus Sumerlaea chitinivorans

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MPDEKPQTHS  DLGNSQAGTP  AASIVILSYN  SASYLGPCLH  SVARLAPPPA  EVIVVDNASR60
DDSVKVAQNV  AAELGLEICT  IPLAGNLGCA  GGNNVGWRAT  RGDIVIFLNP  DTEVSPSFVG120
EVAAAFATDE  RIGIVGAKIY  YPNSNRLQHA  GAIIHPNGQT  DHFGAGETDN  GQFDEPRECD180
YVTGAGFAVR  RQVLTELGGF  DEDFYPAYFE  EVDFCTRARK  RGWRVLYWPR  ATMVHHESVS240
LGVASERFLR  LYHRMRMRYC  AKHFTWKQWV  REFLPRERVA  WRLGSAIDRR  AMRAAYLDLV300
RWRLTRRR308

Predicted 3D structure by AlphaFold2 with pLDDT = 91.22 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MPDEKPQTHS  DLGNSQAGTP  AASIVILSYN  SASYLGPCLH  SVARLAPPPA  EVIVVDNASR60
DDSVKVAQNV  AAELGLEICT  IPLAGNLGCA  GGNNVGWRAT  RGDIVIFLNP  DTEVSPSFVG120
EVAAAFATDE  RIGIVGAKIY  YPNSNRLQHA  GAIIHPNGQT  DHFGAGETDN  GQFDEPRECD180
YVTGAGFAVR  RQVLTELGGF  DEDFYPAYFE  EVDFCTRARK  RGWRVLYWPR  ATMVHHESVS240
LGVASERFLR  LYHRMRMRYC  AKHFTWKQWV  REFLPRERVA  WRLGSAIDRR  AMRAAYLDLV300
RWRLTRRR308

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT2(22-241)

MPDEKPQTHS  DLGNSQAGTP  AASIVILSYN  SASYLGPCLH  SVARLAPPPA  EVIVVDNASR60
DDSVKVAQNV  AAELGLEICT  IPLAGNLGCA  GGNNVGWRAT  RGDIVIFLNP  DTEVSPSFVG120
EVAAAFATDE  RIGIVGAKIY  YPNSNRLQHA  GAIIHPNGQT  DHFGAGETDN  GQFDEPRECD180
YVTGAGFAVR  RQVLTELGGF  DEDFYPAYFE  EVDFCTRARK  RGWRVLYWPR  ATMVHHESVS240
LGVASERFLR  LYHRMRMRYC  AKHFTWKQWV  REFLPRERVA  WRLGSAIDRR  AMRAAYLDLV300
RWRLTRRR308

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help