CAZyme3D

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Entry ID

Information for CAZyme ID: AVQ31353.1

Basic Information

GenBank IDAVQ31353.1
FamilyGT4
Sequence Length344
UniProt IDC6JNS9(99.7,91.9)Download
Average pLDDT?92.31
CAZy50 ID135187
CAZy50 RepYes, AVQ31353.1
Structure ClusterSC_GT4_clus813
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID469618
KingdomBacteria
PhylumFusobacteriota
ClassFusobacteriia
OrderFusobacteriales
FamilyFusobacteriaceae
GenusFusobacterium
SpeciesFusobacterium varium

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MKKKISFIGP  ISQKRNIVGG  ATVKNRYLVE  FLEENGVKLE  ILDTDNWKKN  KIFLLFKLIY60
IFLFSSSKKI  ILSTSSGGTY  LFLKLSYYLN  IRKKLIYYFV  IGGDTPNKLI  EEKYKLKYYK120
KITKIYIETK  SMAQKMKDLG  LIQAEYLPNF  KRFIPKDRSE  KEISLPLKAV  FFSRITYEKG180
TDMIFEMLKE  INKDKININV  DFYGPIDEIY  KNDFHQKISE  FNETEYKGIL  DGRNFKVFDI240
LSEYDFMLFP  TFWKGEGFPG  TIIDSLISSL  PIVSSDWNYN  SEIINSDVGY  IFKSKNQEAF300
NDVIKKILEN  PEKLLKKRRL  SYFESKKYCL  NNVLKNPLEL  LVME344

Predicted 3D structure by AlphaFold2 with pLDDT = 92.31 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MKKKISFIGP  ISQKRNIVGG  ATVKNRYLVE  FLEENGVKLE  ILDTDNWKKN  KIFLLFKLIY60
IFLFSSSKKI  ILSTSSGGTY  LFLKLSYYLN  IRKKLIYYFV  IGGDTPNKLI  EEKYKLKYYK120
KITKIYIETK  SMAQKMKDLG  LIQAEYLPNF  KRFIPKDRSE  KEISLPLKAV  FFSRITYEKG180
TDMIFEMLKE  INKDKININV  DFYGPIDEIY  KNDFHQKISE  FNETEYKGIL  DGRNFKVFDI240
LSEYDFMLFP  TFWKGEGFPG  TIIDSLISSL  PIVSSDWNYN  SEIINSDVGY  IFKSKNQEAF300
NDVIKKILEN  PEKLLKKRRL  SYFESKKYCL  NNVLKNPLEL  LVME344

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT4(170-312)

MEFLEENGVK  LEILDTDNWK  KNKIFLLFKL  IYIFLFSSSK  KIILSTSSGG  TYLFLKLSYY60
LNIRKKLIYY  FVIGGDTPNK  LIEEKYKLKY  YKKITKIYIE  TKSMAQKMKD  LGLIQAEYLP120
NFKRFIPKDR  SEKEISLPLK  AVFFSRITYE  KGTDMIFEML  KEINKDKINI  NVDFYGPIDE180
IYKNDFHQKI  SEFNETEYKG  ILDGRNFKVF  DILSEYDFML  FPTFWKGEGF  PGTIIDSLIS240
SLPIVSSDWN  YNSEIINSDV  GYIFKSKNQE  AFNDVIKKIL  ENPEKLLKKR  RLSYFESKKY300
CLNNVLKNPL  ELLVME316

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help