CAZyme3D

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Entry ID

Information for CAZyme ID: ANZ45852.1

Basic Information

GenBank IDANZ45852.1
FamilyGT4
Sequence Length357
UniProt IDA0A1B2I7A0(100,100)Download
Average pLDDT?95.53
CAZy50 ID128033
CAZy50 RepYes, ANZ45852.1
Structure ClusterSC_GT4_clus864
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID1197717
KingdomBacteria
PhylumSynergistota
ClassSynergistia
OrderSynergistales
FamilySynergistaceae
GenusCloacibacillus
SpeciesCloacibacillus porcorum

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MKILHYVDEN  KLAWGETWIQ  LIHELAVQGV  DNFVVCRPGG  SLPQRLTEEG  IPFAVSTPFI60
QSLPITNLGF  GKILKREKPD  IIHTRLSAAA  RIGGWWGKCY  GIPVVETIDK  YPKIKYYKNA120
SMIFPCSNAV  LQHMEKKGFP  PEKMVVVYNP  VDILRYRRDD  IVRENVRNKY  GVPKDTKIIL180
GAGRFIDWKG  FEYLIDAYFE  VTNNYKTPYD  TRLWLVGDGP  EMKKYRDLSE  KYQLTDRIEF240
HGFARDIRPW  LWAADIFVQP  SQLPEGFSLM  LLEAMAAGLP  SIATNIGGTL  DIIKDGYNGW300
FMGVGIDSGL  AEKLFSVIGD  DQLLSCVALK  ALESANEFNV  RRIAHETITL  YRKILER357

Predicted 3D structure by AlphaFold2 with pLDDT = 95.53 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MKILHYVDEN  KLAWGETWIQ  LIHELAVQGV  DNFVVCRPGG  SLPQRLTEEG  IPFAVSTPFI60
QSLPITNLGF  GKILKREKPD  IIHTRLSAAA  RIGGWWGKCY  GIPVVETIDK  YPKIKYYKNA120
SMIFPCSNAV  LQHMEKKGFP  PEKMVVVYNP  VDILRYRRDD  IVRENVRNKY  GVPKDTKIIL180
GAGRFIDWKG  FEYLIDAYFE  VTNNYKTPYD  TRLWLVGDGP  EMKKYRDLSE  KYQLTDRIEF240
HGFARDIRPW  LWAADIFVQP  SQLPEGFSLM  LLEAMAAGLP  SIATNIGGTL  DIIKDGYNGW300
FMGVGIDSGL  AEKLFSVIGD  DQLLSCVALK  ALESANEFNV  RRIAHETITL  YRKILER357

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT4(172-323)

MKILHYVDEN  KLAWGETWIQ  LIHELAVQGV  DNFVVCRPGG  SLPQRLTEEG  IPFAVSTPFI60
QSLPITNLGF  GKILKREKPD  IIHTRLSAAA  RIGGWWGKCY  GIPVVETIDK  YPKIKYYKNA120
SMIFPCSNAV  LQHMEKKGFP  PEKMVVVYNP  VDILRYRRDD  IVRENVRNKY  GVPKDTKIIL180
GAGRFIDWKG  FEYLIDAYFE  VTNNYKTPYD  TRLWLVGDGP  EMKKYRDLSE  KYQLTDRIEF240
HGFARDIRPW  LWAADIFVQP  SQLPEGFSLM  LLEAMAAGLP  SIATNIGGTL  DIIKDGYNGW300
FMGVGIDSGL  AEKLFSVIGD  DQLLSCVALK  ALESANEFNV  RRIAHETITL  YRKILER357

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help