CAZyme3D

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Entry ID

Information for CAZyme ID: ALC46881.1

Basic Information

GenBank IDALC46881.1
FamilyAA15
Sequence Length237
UniProt IDA0A0M5J779(100,100)Download
Average pLDDT?85.78
CAZy50 ID174921
CAZy50 RepYes, ALC46881.1
Structure ClusterSC_AA15_clus37
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID30019
KingdomEukaryota
PhylumArthropoda
ClassInsecta
OrderDiptera
FamilyDrosophilidae
GenusDrosophila
SpeciesDrosophila busckii

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MRYPLALTCL  LLLMAEIWGH  GMMLDPPSRS  SRWRFDATAP  HNWNDNELFC  GGLYTQIRQG60
GRCGLCGDNF  ALTPPRPNEI  GGQFGGVGII  SQFYATANTI  SVRIKITTNH  LGHFEFQLCN120
LDAFGAETEA  CFSQNRLLFA  DGNNKLEIGT  LTGEFDVLVL  LPKGLICKHC  VLRWTYVGGK180
LNFTYYTYRI  ELKLFLTKAN  NWGICDNGIG  ALGCGPQETF  KNCADVSIYN  ADNIWRE237

Predicted 3D structure by AlphaFold2 with pLDDT = 85.78 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MRYPLALTCL  LLLMAEIWGH  GMMLDPPSRS  SRWRFDATAP  HNWNDNELFC  GGLYTQIRQG60
GRCGLCGDNF  ALTPPRPNEI  GGQFGGVGII  SQFYATANTI  SVRIKITTNH  LGHFEFQLCN120
LDAFGAETEA  CFSQNRLLFA  DGNNKLEIGT  LTGEFDVLVL  LPKGLICKHC  VLRWTYVGGK180
LNFTYYTYRI  ELKLFLTKAN  NWGICDNGIG  ALGCGPQETF  KNCADVSIYN  ADNIWRE237

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : AA15(20-226)

MRYPLALTCL  LLLMAEIWGH  GMMLDPPSRS  SRWRFDATAP  HNWNDNELFC  GGLYTQIRQG60
GRCGLCGDNF  ALTPPRPNEI  GGQFGGVGII  SQFYATANTI  SVRIKITTNH  LGHFEFQLCN120
LDAFGAETEA  CFSQNRLLFA  DGNNKLEIGT  LTGEFDVLVL  LPKGLICKHC  VLRWTYVGGK180
LNFTYYTYRI  ELKLFLTKAN  NWGICDNGIG  ALGCGPQETF  KNCADVSIYN  ADNIWRE237

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help

qseqidqlensseqidpidentevaluelengthqstartqendqcovhspscovhsp
ALC46881.1237ALC46881.11004.11e-1922371237100100