CAZyme3D

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Entry ID

Information for CAZyme ID: AGB41821.1

Basic Information

GenBank IDAGB41821.1
FamilyCBM50
Sequence Length234
UniProt IDL0KA00(100,100)Download
Average pLDDT?76.23
CAZy50 ID175510
CAZy50 RepYes, AGB41821.1
Structure ClusterSC_CBM50_clus32
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID748449
KingdomBacteria
PhylumBacillota
ClassClostridia
OrderHalanaerobiales
FamilyHalobacteroidaceae
GenusHalobacteroides
SpeciesHalobacteroides halobius

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MKKIKFWLVL  SLVLGLLVGN  TISINAQNYR  QQDQNQNLLC  IIKYGDSLWK  ISQRYDINLE60
KIIQANPQIE  DPNLIYPGDR  IYETKGQRQR  KEQKQPEKER  QQQPTSLKAM  EKKIVALVNQ120
ERQKQGLKPY  QHNPKLSKVA  RTKAQDMVKN  NYFSHTSPTY  GSPFEMLSQF  NVSYRTAGEN180
IAQGQRTAQQ  VMNAWMNSPG  HRRNILNQRF  TQIGVGLAKD  EDGTPYWVQM  FIKP234

Predicted 3D structure by AlphaFold2 with pLDDT = 76.23 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MKKIKFWLVL  SLVLGLLVGN  TISINAQNYR  QQDQNQNLLC  IIKYGDSLWK  ISQRYDINLE60
KIIQANPQIE  DPNLIYPGDR  IYETKGQRQR  KEQKQPEKER  QQQPTSLKAM  EKKIVALVNQ120
ERQKQGLKPY  QHNPKLSKVA  RTKAQDMVKN  NYFSHTSPTY  GSPFEMLSQF  NVSYRTAGEN180
IAQGQRTAQQ  VMNAWMNSPG  HRRNILNQRF  TQIGVGLAKD  EDGTPYWVQM  FIKP234

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : CBM50(41-81)

MKKIKFWLVL  SLVLGLLVGN  TISINAQNYR  QQDQNQNLLC  IIKYGDSLWK  ISQRYDINLE60
KIIQANPQIE  DPNLIYPGDR  IYETKGQRQR  KEQKQPEKER  QQQPTSLKAM  EKKIVALVNQ120
ERQKQGLKPY  QHNPKLSKVA  RTKAQDMVKN  NYFSHTSPTY  GSPFEMLSQF  NVSYRTAGEN180
IAQGQRTAQQ  VMNAWMNSPG  HRRNILNQRF  TQIGVGLAKD  EDGTPYWVQM  FIKP234

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help