CAZyme3D

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Entry ID

Information for CAZyme ID: AEE91286.1

Basic Information

GenBank IDAEE91286.1
FamilyGT28
Sequence Length374
UniProt IDF4LT17(100,100)Download
Average pLDDT?91.46
CAZy50 ID116387
CAZy50 RepYes, AEE91286.1
Structure ClusterSC_GT28_clus70
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID1209989
KingdomBacteria
PhylumBacillota
ClassClostridia
OrderThermosediminibacterales
FamilyTepidanaerobacteraceae
GenusTepidanaerobacter
SpeciesTepidanaerobacter acetatoxydans

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MPPKKNKKII  LAGGGTGGHI  YPAIAIATGL  KQEFPDSDIL  FIGTNKGLEK  ELVKKAGFSL60
KTIRVKGFQR  KLSFDTIISV  KELALSAIDS  VNIIKKEKPD  IVIGTGGYVA  GPVVFFASLM120
GVHTAIHEQN  VTPGITNRIL  SKFVEKVFIS  FPDSLKYFPK  NKTVLTGNPV  RNEITKSIRS180
QALKKFGLLL  NIPTVLCFGG  SQGAARLNDA  ILYIINEIKD  TKRFQLIHIT  GINHYEKTID240
LLANKGIDLS  KLGHIIIRPY  IHEMQDAYAV  ADLVISRAGA  LSISELNACG  KPAILIPLPT300
AANRHQDFNA  KFMEENGAAI  VISEASLSGE  KLLDTISNII  FDQKRLHQMA  AASKNLARED360
ALEKILAEIV  KLVK374

Predicted 3D structure by AlphaFold2 with pLDDT = 91.46 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MPPKKNKKII  LAGGGTGGHI  YPAIAIATGL  KQEFPDSDIL  FIGTNKGLEK  ELVKKAGFSL60
KTIRVKGFQR  KLSFDTIISV  KELALSAIDS  VNIIKKEKPD  IVIGTGGYVA  GPVVFFASLM120
GVHTAIHEQN  VTPGITNRIL  SKFVEKVFIS  FPDSLKYFPK  NKTVLTGNPV  RNEITKSIRS180
QALKKFGLLL  NIPTVLCFGG  SQGAARLNDA  ILYIINEIKD  TKRFQLIHIT  GINHYEKTID240
LLANKGIDLS  KLGHIIIRPY  IHEMQDAYAV  ADLVISRAGA  LSISELNACG  KPAILIPLPT300
AANRHQDFNA  KFMEENGAAI  VISEASLSGE  KLLDTISNII  FDQKRLHQMA  AASKNLARED360
ALEKILAEIV  KLVK374

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT115(14-167)+GT28(194-361)

MPPKKNKKII  LAGGGTGGHI  YPAIAIATGL  KQEFPDSDIL  FIGTNKGLEK  ELVKKAGFSL60
KTIRVKGFQR  KLSFDTIISV  KELALSAIDS  VNIIKKEKPD  IVIGTGGYVA  GPVVFFASLM120
GVHTAIHEQN  VTPGITNRIL  SKFVEKVFIS  FPDSLKYFPK  NKTVLTGNPV  RNEITKSIRS180
QALKKFGLLL  NIPTVLCFGG  SQGAARLNDA  ILYIINEIKD  TKRFQLIHIT  GINHYEKTID240
LLANKGIDLS  KLGHIIIRPY  IHEMQDAYAV  ADLVISRAGA  LSISELNACG  KPAILIPLPT300
AANRHQDFNA  KFMEENGAAI  VISEASLSGE  KLLDTISNII  FDQKRLHQMA  AASKNLARED360
ALEKILAEIV  KLVK374

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help

qseqidqlensseqidpidentevaluelengthqstartqendqcovhspscovhsp
AEE91286.1374AEE91286.11001.86e-2693741374100100