CAZyme3D

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Entry ID

Information for CAZyme ID: AEB14948.1

Basic Information

GenBank IDAEB14948.1
FamilyGT104
Sequence Length415
UniProt IDF2NTF9(100,100)Download
Average pLDDT?89.20
CAZy50 ID91436
CAZy50 RepYes, AEB14948.1
Structure ClusterSC_GT104_clus3
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID869209
KingdomBacteria
PhylumSpirochaetota
ClassSpirochaetia
OrderSpirochaetales
FamilyTreponemataceae
GenusTreponema
SpeciesTreponema succinifaciens

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MEKIKKMPQI  KKNLIKCFFM  EITVLCKVVD  NFGDIGVVFR  LCRALSELKK  NLEIRLVVSN60
LDSFAKISKG  IDSTKTFQEF  RGWKVFDWND  SALCKKEFSK  NPPEFILECF  QCGRPEWLEE120
LLFSQQFNLN  VQIVNVEYLT  AESWADDFHL  LKSGTRSAKI  KKINFMPGFT  KKTGGLILDK180
NFMRCLSEKK  FALNLVKQNL  DKKILSEDFS  DSFKILIFSY  PKNFDFLASA  IKEFSFLKKI240
IVFVASGAGA  DSAKISLKKF  KVDFVCLPFM  QQEVWDAFLS  LMDFSFVRGE  DSFSRCCLFG300
NPFIWNIYSQ  EEEFHIVKLN  AFLQKIKIPQ  IEKFSFLYNR  SFKASCCPES  LEILEEKKLP360
SELEKINSEM  KTEILSLLKN  YESLKPEFKK  FSNEILKNGN  LAENLLNLLE  TKIPR415

Predicted 3D structure by AlphaFold2 with pLDDT = 89.20 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MEKIKKMPQI  KKNLIKCFFM  EITVLCKVVD  NFGDIGVVFR  LCRALSELKK  NLEIRLVVSN60
LDSFAKISKG  IDSTKTFQEF  RGWKVFDWND  SALCKKEFSK  NPPEFILECF  QCGRPEWLEE120
LLFSQQFNLN  VQIVNVEYLT  AESWADDFHL  LKSGTRSAKI  KKINFMPGFT  KKTGGLILDK180
NFMRCLSEKK  FALNLVKQNL  DKKILSEDFS  DSFKILIFSY  PKNFDFLASA  IKEFSFLKKI240
IVFVASGAGA  DSAKISLKKF  KVDFVCLPFM  QQEVWDAFLS  LMDFSFVRGE  DSFSRCCLFG300
NPFIWNIYSQ  EEEFHIVKLN  AFLQKIKIPQ  IEKFSFLYNR  SFKASCCPES  LEILEEKKLP360
SELEKINSEM  KTEILSLLKN  YESLKPEFKK  FSNEILKNGN  LAENLLNLLE  TKIPR415

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT104(22-411)

MEKIKKMPQI  KKNLIKCFFM  EITVLCKVVD  NFGDIGVVFR  LCRALSELKK  NLEIRLVVSN60
LDSFAKISKG  IDSTKTFQEF  RGWKVFDWND  SALCKKEFSK  NPPEFILECF  QCGRPEWLEE120
LLFSQQFNLN  VQIVNVEYLT  AESWADDFHL  LKSGTRSAKI  KKINFMPGFT  KKTGGLILDK180
NFMRCLSEKK  FALNLVKQNL  DKKILSEDFS  DSFKILIFSY  PKNFDFLASA  IKEFSFLKKI240
IVFVASGAGA  DSAKISLKKF  KVDFVCLPFM  QQEVWDAFLS  LMDFSFVRGE  DSFSRCCLFG300
NPFIWNIYSQ  EEEFHIVKLN  AFLQKIKIPQ  IEKFSFLYNR  SFKASCCPES  LEILEEKKLP360
SELEKINSEM  KTEILSLLKN  YESLKPEFKK  FSNEILKNGN  LAENLLNLLE  TKIPR415

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help