CAZyme3D

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Entry ID

Information for CAZyme ID: AAO75158.1

Basic Information

GenBank IDAAO75158.1
FamilyGT2
Sequence Length326
UniProt IDQ8ABQ9(100,100)Download
Average pLDDT?94.13
CAZy50 ID143895
CAZy50 RepYes, AAO75158.1
Structure ClusterSC_GT2_clus837
EC Number(s)-
Substrates(s)-

Taxonomy

Tax ID226186
KingdomBacteria
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides thetaiotaomicron

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MVVSIITPLY  KVEDFIARCA  DSLFRQSYTE  IEYIFVDDCS  SDRSVEVLLQ  VAERYPQLQQ60
QIRILHHESN  RGVAAARETG  LAAATGEYVY  WVDADDWIEP  DAIEKMVVRS  EQGQKDIIAC120
GWYLCFRQNE  RRMPMPCYAD  AETALRGMLS  GTMRWNLWLY  MIKRDLYLMN  DIHFMEGENV180
GEDMLVLIKL  FSHAKSIGFV  KDAFYHYVKQ  NENSLTRLSP  EQQMKRQMRN  LQAATDYLVT240
HFIGKYEKEI  NFFKLNAKMP  LLISNDKNSY  RTWTACFPEA  NKYIMANKRQ  TLRMRLVQLM300
AAKRQFWLVE  LYYQLVFKFV  YGILYK326

Predicted 3D structure by AlphaFold2 with pLDDT = 94.13 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MVVSIITPLY  KVEDFIARCA  DSLFRQSYTE  IEYIFVDDCS  SDRSVEVLLQ  VAERYPQLQQ60
QIRILHHESN  RGVAAARETG  LAAATGEYVY  WVDADDWIEP  DAIEKMVVRS  EQGQKDIIAC120
GWYLCFRQNE  RRMPMPCYAD  AETALRGMLS  GTMRWNLWLY  MIKRDLYLMN  DIHFMEGENV180
GEDMLVLIKL  FSHAKSIGFV  KDAFYHYVKQ  NENSLTRLSP  EQQMKRQMRN  LQAATDYLVT240
HFIGKYEKEI  NFFKLNAKMP  LLISNDKNSY  RTWTACFPEA  NKYIMANKRQ  TLRMRLVQLM300
AAKRQFWLVE  LYYQLVFKFV  YGILYK326

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT2(4-180)

MVVSIITPLY  KVEDFIARCA  DSLFRQSYTE  IEYIFVDDCS  SDRSVEVLLQ  VAERYPQLQQ60
QIRILHHESN  RGVAAARETG  LAAATGEYVY  WVDADDWIEP  DAIEKMVVRS  EQGQKDIIAC120
GWYLCFRQNE  RRMPMPCYAD  AETALRGMLS  GTMRWNLWLY  MIKRDLYLMN  DIHFMEGENV180
GEDMLVLIKL  FSHAKSIGFV  KDAFYHYVKQ  NENSLTRLSP  EQQMKRQMRN  LQAATDYLVT240
HFIGKYEKEI  NFFKLNAKMP  LLISNDKNSY  RTWTACFPEA  NKYIMANKRQ  TLRMRLVQLM300
AAKRQFWLVE  LYYQLVFKFV  YGILYK326

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help