CAZyme3D

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Entry ID

Information for CAZyme ID: AAF56843.1

Basic Information

GenBank IDAAF56843.1
FamilyGT7
Sequence Length323
UniProt IDQ9VAQ8(100,100)Download
Average pLDDT?93.36
CAZy50 ID145325
CAZy50 RepYes, AAF56843.1
Structure ClusterSC_GT7_clus49
EC Number(s)2.4.1.-
Substrates(s)-

Taxonomy

Tax ID7227
KingdomEukaryota
PhylumArthropoda
ClassInsecta
OrderDiptera
FamilyDrosophilidae
GenusDrosophila
SpeciesDrosophila melanogaster

Protein Sequence:
90 < plddt <=100;
70 < plddt <= 90;
50 < plddt <= 70;
0 <= plddt <= 50;     Download help

MFVRLWVRSF  HKYDLLIAIG  LITLIVYLCL  PFRFASHYDY  IEESKIEGAL  VPQVTRNVSQ60
QEVFECTYSE  IIAENRFVYH  LAHYHDAVQR  GAEIRPGGEF  RPEGCQARYS  TAIIVPYRQR120
EEQLHAFLTY  MHNYLPQQLI  HYRIFLVEQF  DHKPFNRAML  FNIGAQVAAE  YGFPCLILHD180
VDLLPLNSGQ  IYACSERPRH  MSSALDHWRF  RLPYRGLFGG  VVAINTAQYQ  QINGMSNLYY240
GWGGEDDDLY  ERLQALNIDI  CRFAMEFSKY  TMLKHKQEQP  NANRVALLRS  ATLRQHADGL300
NSLVYTEMER  RMHSLFTHIL  VDT323

Predicted 3D structure by AlphaFold2 with pLDDT = 93.36 ; Download help

pLDDT is for per-residue accuracy of the structure, which representes the quality of the residue. A higher value indicates better prediction accuracy. More detail please see AlphaFold .

Residues were colored according to plddt ( blue-> high quality; red-> low quality ).

Full Sequence:
CAPSIF:V and CAPSIF:G =99.9;
CAPSIF:V =59.9;
CAPSIF:G =40;
Non-Binding=0;     Download help

MFVRLWVRSF  HKYDLLIAIG  LITLIVYLCL  PFRFASHYDY  IEESKIEGAL  VPQVTRNVSQ60
QEVFECTYSE  IIAENRFVYH  LAHYHDAVQR  GAEIRPGGEF  RPEGCQARYS  TAIIVPYRQR120
EEQLHAFLTY  MHNYLPQQLI  HYRIFLVEQF  DHKPFNRAML  FNIGAQVAAE  YGFPCLILHD180
VDLLPLNSGQ  IYACSERPRH  MSSALDHWRF  RLPYRGLFGG  VVAINTAQYQ  QINGMSNLYY240
GWGGEDDDLY  ERLQALNIDI  CRFAMEFSKY  TMLKHKQEQP  NANRVALLRS  ATLRQHADGL300
NSLVYTEMER  RMHSLFTHIL  VDT323

Carbohydrate binding residues Predicted by CAPSIF from 3D structure; Download help

Residues were colored according to prediction score:

Nonbinder, CAPSIF:G Predicted Binder, CAPSIF:V Predicted Binder, CAPSIF:V and CAPSIF:G Predicted Binder

CArbohydrate–Protein interaction Site IdentiFier (CAPSIF) that predicts non-covalent carbohydrate-binding sites on proteins: (1) a 3D-UNet voxel-based neural network model (CAPSIF:V) and (2) an equivariant graph neural network model (CAPSIF:G).

Details:
⋆B-Factor = 0.0 : Nonbinder.
⋆B-Factor = 40.0 : CAPSIF:G Predicted Binder.
⋆B-Factor = 59.9 : CAPSIF:V Predicted Binder.
⋆B-Factor = 99.9 : CAPSIF:V and CAPSIF:G Predicted Binder.

For more detail please see CAPSIF.

Full Sequence:
AA;
CE;
PL;
GH;
GT;
CBM;     Download structure help

dbCAN3 predicted domain(s) : GT7(86-322)

MFVRLWVRSF  HKYDLLIAIG  LITLIVYLCL  PFRFASHYDY  IEESKIEGAL  VPQVTRNVSQ60
QEVFECTYSE  IIAENRFVYH  LAHYHDAVQR  GAEIRPGGEF  RPEGCQARYS  TAIIVPYRQR120
EEQLHAFLTY  MHNYLPQQLI  HYRIFLVEQF  DHKPFNRAML  FNIGAQVAAE  YGFPCLILHD180
VDLLPLNSGQ  IYACSERPRH  MSSALDHWRF  RLPYRGLFGG  VVAINTAQYQ  QINGMSNLYY240
GWGGEDDDLY  ERLQALNIDI  CRFAMEFSKY  TMLKHKQEQP  NANRVALLRS  ATLRQHADGL300
NSLVYTEMER  RMHSLFTHIL  VDT323

Predicted CAZyme domains from dbCAN; Download help

Domains were colored according to CAZyme classification: (AA), (CE), (PL), (GH), (GT), (CBM), & (Null)

dbCAN3 server is a web server for automated Carbohydrate-active enzyme ANnotation.

Details:
dbCAN3 server integrates three state-of-the-art tools/databases for automated CAZyme annotation:
⋆HMMER search for CAZyme family annotation vs. dbCAN CAZyme domain HMM database
⋆DIAMOND search for BLAST hits in the CAZy database
⋆HMMER search for CAZyme subfamily annotation vs. dbCAN-sub HMM database of CAZyme subfamilies (derived from eCAMI classification of CAZyDB families)

For more details, please see dbCAN3.

Similarites between the same cluster seqeunces from DIAMOND; Download help