| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s171_117V6.1 |
| Family | GT47 |
| Protein Properties | Length: 437 Molecular Weight: 49853.6 Isoelectric Point: 6.7048 |
| Chromosome | Chromosome/Scaffold: 171 Start: 700190 End: 701713 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 124 | 392 | 5.20022e-42 |
| LQIWVYPSQAGNTSYEHKFDGRKDVMEELSSTADLFSRLLLRSKFSTELPQKAQLFLLPFSIDALRVDLGPSRISDHLRRYVQNVRTSYPYWNLSLGANH FYLSSQAFENNNKHRNVLELEKNSIQAACAPLRQNQNFYPHKDFIFPRYKPITQTEFYAALEGRTSRTVLAYFGGTLADTPALVFILDAWKSDPDFEVEV DPSPHRISVYRQLARSKFCVNVPSRDTFDFVDAIRFGCVLVLLSKSVFLDLPFQGFLDWRQFAYLGHEA | |||
| Full Sequence |
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| Protein Sequence Length: 437 Download |
| MPIDGYRCAS RSLKLGLKEI AVTFEVKASG GLHFYLSVTF SSSGIIQDGS SGSLLSHERV 60 LASAESEDKV EELAEIGAMV STPDPVSVWD MAEPDFLALH RSLPKLYHSP EVFTLSYEEM 120 WIQLQIWVYP SQAGNTSYEH KFDGRKDVME ELSSTADLFS RLLLRSKFST ELPQKAQLFL 180 LPFSIDALRV DLGPSRISDH LRRYVQNVRT SYPYWNLSLG ANHFYLSSQA FENNNKHRNV 240 LELEKNSIQA ACAPLRQNQN FYPHKDFIFP RYKPITQTEF YAALEGRTSR TVLAYFGGTL 300 ADTPALVFIL DAWKSDPDFE VEVDPSPHRI SVYRQLARSK FCVNVPSRDT FDFVDAIRFG 360 CVLVLLSKSV FLDLPFQGFL DWRQFAYLGH EARKHLEWNN PPVPYDAFYM TLLELWERRH 420 SIKCGRRNLN SATAVS* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-27 | 170 | 387 | 231 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001753053.1 | 0 | 43 | 427 | 51 | 462 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001774055.1 | 0 | 18 | 386 | 41 | 409 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001774096.1 | 0 | 104 | 423 | 1 | 350 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002268836.1 | 1.99993e-41 | 105 | 423 | 77 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311191.1 | 9.99967e-42 | 106 | 427 | 26 | 342 | predicted protein [Populus trichocarpa] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CN206190 | 250 | 138 | 386 | 0 |
| CN202331 | 167 | 99 | 265 | 8e-36 |
| EG631217 | 362 | 97 | 427 | 2e-34 |
| EX381460 | 252 | 98 | 344 | 2e-33 |
| CO105146 | 274 | 179 | 423 | 9e-32 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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