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CAZyme Information: MGYG000004697_01640
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eubacterium_F; | |||||||||||
| CAZyme ID | MGYG000004697_01640 | |||||||||||
| CAZy Family | GH11 | |||||||||||
| CAZyme Description | Bifunctional xylanase/deacetylase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 15576; End: 16691 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH11 | 40 | 221 | 5.9e-76 | 0.9887005649717514 |
| CBM36 | 257 | 368 | 4.7e-47 | 0.9739130434782609 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00457 | Glyco_hydro_11 | 4.92e-83 | 40 | 220 | 1 | 175 | Glycosyl hydrolases family 11. |
| cd04078 | CBM36_xylanase-like | 1.52e-56 | 255 | 371 | 3 | 119 | Carbohydrate Binding Module family 36 (CBM36); appended mainly to glycoside hydrolase family 11 (GH11) domains; xylan binding. This family includes carbohydrate binding module family 36 (CBM36) most of which appear appended to glycoside hydrolase family 11 (GH11) domains. These CBMs are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH11 catalytic modules with their dedicated, insoluble substrates. GH11 domains have xylanase (endo-1,4-beta-xylanase) activity which catalyzes the hydrolysis of beta-1,4 bonds of xylan, the major component of hemicelluloses, to generate xylooligosaccharides and xylose. This family includes XynB from Dictyoglomus thermophilum Rt46B.1 and Xyn11A from Pseudobutyrivibrio xylanivorans Mz5T. Xyn11A is a multicatalytic enzyme with an N-terminal GH11 domain, a CBM36 domain, and a C-terminal putative NodB-like polysaccharide deacetylase which is predicted to be an acetyl esterase involved in debranching activity in the xylan backbone. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. Consistent with its structural and sequence similarity to CBM6, CBM36 binds xylan, but only at binding site I, and in a calcium-dependent manner; the latter suggests its potential application in affinity labeling. |
| pfam03422 | CBM_6 | 0.008 | 273 | 369 | 20 | 122 | Carbohydrate binding module (family 6). |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CUH92232.1 | 1.74e-190 | 1 | 368 | 1 | 367 |
| QJT73074.1 | 2.29e-188 | 14 | 369 | 1 | 346 |
| ASR48765.1 | 7.20e-183 | 1 | 368 | 1 | 358 |
| AYV88966.1 | 2.10e-182 | 21 | 368 | 20 | 368 |
| CAD65888.2 | 3.94e-182 | 14 | 368 | 1 | 363 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7AYP_A | 2.19e-182 | 28 | 368 | 1 | 350 | Structureof a GH11 domain refined from the X-ray diffraction data of a GH11-CBM36-1 crystal. [uncultured bacterium] |
| 2DCJ_A | 5.32e-161 | 1 | 368 | 1 | 351 | Atwo-domain structure of alkaliphilic XynJ from Bacillus sp. 41M-1 [Bacillus sp. 41M-1],2DCJ_B A two-domain structure of alkaliphilic XynJ from Bacillus sp. 41M-1 [Bacillus sp. 41M-1],2DCK_A A tetragonal-lattice structure of alkaliphilic XynJ from Bacillus sp. 41M-1 [Bacillus sp. 41M-1] |
| 6KKA_A | 4.76e-160 | 31 | 368 | 2 | 324 | XylanaseJ mutant from Bacillus sp. 41M-1 [Bacillus sp. 41M-1],6KKA_B Xylanase J mutant from Bacillus sp. 41M-1 [Bacillus sp. 41M-1] |
| 6KJL_A | 7.00e-160 | 31 | 368 | 3 | 325 | XylanaseJ from Bacillus sp. strain 41M-1 [Bacillus sp. 41M-1],6KJL_B Xylanase J from Bacillus sp. strain 41M-1 [Bacillus sp. 41M-1] |
| 7AYL_A | 1.37e-130 | 9 | 230 | 10 | 231 | Crystalstructure of the GH11 domain of a multidomain xylanase from the hindgut metagenome of Trinervitermes trinervoides [uncultured bacterium],7AYL_B Crystal structure of the GH11 domain of a multidomain xylanase from the hindgut metagenome of Trinervitermes trinervoides [uncultured bacterium] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P83513 | 7.88e-183 | 14 | 368 | 1 | 363 | Bifunctional xylanase/deacetylase OS=Pseudobutyrivibrio xylanivorans OX=185007 GN=xyn11A PE=1 SV=2 |
| Q8GJ44 | 4.80e-111 | 11 | 355 | 14 | 359 | Endo-1,4-beta-xylanase A OS=Thermoclostridium stercorarium OX=1510 GN=xynA PE=1 SV=2 |
| P17137 | 5.64e-111 | 24 | 229 | 55 | 260 | Endo-1,4-beta-xylanase OS=Clostridium saccharobutylicum OX=169679 GN=xynB PE=3 SV=1 |
| P33558 | 8.78e-108 | 11 | 355 | 14 | 360 | Endo-1,4-beta-xylanase A OS=Thermoclostridium stercorarium OX=1510 GN=xynA PE=1 SV=2 |
| P00694 | 2.95e-100 | 1 | 229 | 1 | 227 | Endo-1,4-beta-xylanase A OS=Bacillus pumilus OX=1408 GN=xynA PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000216 | 0.999217 | 0.000152 | 0.000166 | 0.000143 | 0.000135 |
