CAZyme Information: MGYG000004455_01025

Basic Information

• Lineage: Bacteria; Firmicutes; Bacilli; RF39; UBA660; CAG-877
• CAZyme ID: MGYG000004455_01025
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
383		42763.69	5.1903

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004455	1511314	MAG	Israel	Asia

• Gene Location: Start: 79282; End: 80433 Strand: +

Full Sequence      

MKKVLIVVLGVMVVGLLGFVFTNNGKVDNKSNKDIKVNKNINSNELFSKEYESAQVKLDN
MTLEEKVGQLFLVRYDKNMALSWINDYYAGGYILFAKDFDNHTKESIKEELSSLNKNSKI
PMVFAVDEEGGYVTRVSRYKAFRDEKFPSPRDVYDSLGVEGLESIEKEKGELLLSLGINL
NLAPVADVSVDSNDFINIRTFNRDAKETANLIGLMVDYANEVGISSSLKHFPGYGNNVDT
HTGVAIDERSYDNFLNNDYLPFEEGIKRKVPSILVSHNIIKCIDSEYPATLSKKIVTGEL
RNKLNFSGIIITDDLSMGAVSSYVDDNSAAVLAINAGNDLIITSDFVNMYNSVITAVKAG
KIKRETIDTAVRRILAWKSFYNM

Enzyme Prediction     

No EC number prediction in MGYG000004455_01025.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	115	342	8.9e-41	0.9768518518518519

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00933	Glyco_hydro_3	1.59e-64	62	375	1	314	Glycosyl hydrolase family 3 N terminal domain.
COG1472	BglX	7.27e-57	61	381	1	315	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
PRK05337	PRK05337	1.38e-33	90	341	27	277	beta-hexosaminidase; Provisional
PRK15098	PRK15098	1.65e-18	58	383	42	356	beta-glucosidase BglX.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QHQ63470.1	4.07e-110	54	378	85	408
ASW43722.1	4.57e-110	1	378	1	382
SET88834.1	4.95e-106	60	378	96	411
BCI61427.1	3.50e-105	52	383	151	481
ABX42693.1	4.82e-104	46	383	68	405

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6K5J_A	3.12e-38	61	378	11	337	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3BMX_A	3.56e-36	48	378	29	393	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
3LK6_A	1.43e-35	48	378	3	367	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]
4GYJ_A	1.74e-35	48	378	33	397	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
7VI6_A	3.43e-31	91	340	28	273	ChainA, Beta-N-acetylhexosaminidase [Akkermansia muciniphila ATCC BAA-835],7VI6_B Chain B, Beta-N-acetylhexosaminidase [Akkermansia muciniphila ATCC BAA-835],7VI7_A Chain A, Beta-N-acetylhexosaminidase [Akkermansia muciniphila ATCC BAA-835],7VI7_B Chain B, Beta-N-acetylhexosaminidase [Akkermansia muciniphila ATCC BAA-835]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	1.95e-35	48	378	29	393	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	3.30e-34	84	379	59	381	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
P44955	1.16e-31	89	342	26	277	Beta-hexosaminidase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=nagZ PE=3 SV=1
A5UDA9	7.84e-30	89	342	26	277	Beta-hexosaminidase OS=Haemophilus influenzae (strain PittEE) OX=374930 GN=nagZ PE=3 SV=1
Q4QLU8	1.10e-29	89	342	26	277	Beta-hexosaminidase OS=Haemophilus influenzae (strain 86-028NP) OX=281310 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.786261	0.180667	0.031700	0.000362	0.000246	0.000773

TMHMM  Annotations     

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