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CAZyme Information: MGYG000004241_00753

You are here: Home > Sequence: MGYG000004241_00753

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes sp900761235
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; Alistipes sp900761235
CAZyme ID MGYG000004241_00753
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
731 MGYG000004241_4|CGC1 82687.93 6.1236
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004241 2156541 MAG United Kingdom Europe
Gene Location Start: 36904;  End: 39099  Strand: -

Full Sequence      Download help

MNFKRLLSVA  AAAALSVSVS  AQSLRSPDGN  LELRFAIAEG  GVPTYSLSYK  DREVVRPSAL60
GFEFVEDAYA  TFGDFNSKRE  KDVFPMNRGF  VSLGSEQSSF  DETWTPVWGE  NAEIRNHYNE120
MLVRLCRDDR  GYLMNIRFRL  YDDGMGLRYE  FPEQKDLTYF  VIAEERTQFA  MTGDHTAYWI180
AGDYDTQEYD  YTVSRLSEIR  SLLPKAVCGN  SSQQIFSPTG  VQTALQLKTD  DGLYLNIHEA240
ALVDYSCMHL  DLDDRNFVFT  SHLTPDAQGY  KGWMQAPCHT  PWRSVTVTDN  ACDMLASNLT300
LNLNDPCVLE  DTSWIKPVKY  VGVWWEMISG  KSDWAYTAEY  PAVQLGVTDY  ANAKPSGRHA360
ANNANVRRYI  DFAAEHGFDQ  VLVEGWNIGW  EDWAGKKKDY  VFDFVTPYPD  FDIAALNEYA420
QSKGVRLMMH  HETSSSVRNY  ERHMEKAYSL  MNRYGYNAVK  SGYVGDIVPR  GEHHYGQWMV480
NHYLYAVKEA  AKHRVMVNAH  EAVRPTGLCR  TYPNLIGNES  ARGTEYQAFG  GSKPHHVTIL540
PFTRLKGGPM  DYTPGIFEMD  VKKVSGGKTD  SWVNATICNQ  LALYVTMYSP  LQMAADLPEH600
YERYADAFRF  IKDVAVDWRR  SRYLAAEPGE  YIVAARQAKE  SGDWFVGGVT  NGERRTMPVA660
LDFLDPSKSY  VATLYADSTD  ADYKTKPDGY  VITSGRVDSR  SVLKIAMARG  GGFAISIREA720
TDADRKLKRL  R731

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap367310914618221925529232836540243847551154858462165769413717GH97
Family Start End Evalue family coverage
GH97 13 717 1.5e-240 0.9889064976228209

CDD Domains      download full data without filtering help

Created with Snap3673109146182219255292328365402438475511548584621657694311615Glyco_hydro_9726306GH97_N618718GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 2.49e-142 311 615 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 9.10e-93 26 306 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 2.22e-38 618 718 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap36731091461822192552923283654024384755115485846216576944731BBL00134.1|GH974731AFL78247.1|GH974731CBK62784.1|GH974731BBL08215.1|GH974731BBL11006.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
BBL00134.1 0.0 4 731 3 731
AFL78247.1 0.0 4 731 3 731
CBK62784.1 0.0 4 731 3 731
BBL08215.1 0.0 4 731 3 731
BBL11006.1 0.0 4 731 3 731

PDB Hits      download full data without filtering help

Created with Snap3673109146182219255292328365402438475511548584621657694227302D73_A247302JKA_A227303WFA_A237155HQ4_A237155HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 22 730 23 738
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 24 730 14 727
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 22 730 3 718
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 1.49e-163 23 715 2 656
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 1.49e-163 23 715 2 656
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36731091461822192552923283654024384755115485846216576941730sp|G8JZS4|SUSB_BACTN16718sp|Q8A6L0|AGAL_BACTN18714sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 1 730 1 738
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 3.97e-68 16 718 14 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 9.75e-37 18 714 36 617
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000513 0.998408 0.000333 0.000241 0.000243 0.000220

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004241_00753.