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CAZyme Information: MGYG000004199_00402

You are here: Home > Sequence: MGYG000004199_00402

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes; Bacilli; RFN20; CAG-449; CAG-449;
CAZyme ID MGYG000004199_00402
CAZy Family GH94
CAZyme Description Cellobiose phosphorylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
746 MGYG000004199_6|CGC1 86092.99 6.3674
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004199 1652569 MAG United Kingdom Europe
Gene Location Start: 22907;  End: 25147  Strand: +

Full Sequence      Download help

MIKTNTGYFD  KLNNEYVITN  MKPIRPLKNF  LFNEKMIGSY  DQFGFGLSQG  QTPSGFRNLL60
MDYRLIYIKE  GESYYCANRN  FTDLPFDIFE  CHVGIGYQKI  VSQYQGIQVE  LNIVIPRQDY120
CEINHVVVKN  TTDRTREIKL  VYVNKPFVNL  TWHTAYTYAD  YNKENNALVF  SHLGYDVDEK180
NNIVLIKPSL  NIDSFDVSEI  NFKGIYNSLS  DPKALKNEHL  SNTPMTFDYE  NAGCMMFNLV240
IGPKEKKSIN  VVSCFGESFN  EANEVASKYI  DEKSYVEEMR  QLKQQNDNQR  AHFEVETPDE300
YLNIMMNTFL  KRQIDLGKTW  GRVYGKGFRD  VMQDTASFTS  LDPLKAKEKI  INTLKYQFEN360
GNTIRQFDPV  LDYPYQDGAS  WICYALLTYL  KETNDLSILS  IDVNYYQSDK  KESVFLHAKK420
GIDYLLNNLG  KHNLVLWGGG  DWNDSLNNCG  MKGIGESVWL  SMATIKATRE  FLYITERTSL480
QVNREYYLNK  IDILNDAIMK  YGFEEDQFIY  GFNDYGKKIG  SKYEKEGSIF  LNPQTWAVLA540
NVGSIKEQNK  VMNNVEEKLK  CSFGYMQLAP  SFSKGDDNIG  RASYFLPGTY  ENGSVYNHGV600
AFKIAADYAL  NRNDNAYETL  KMISPIYNQN  SGMEPYAYGN  MYLGPECISR  VGFSPMPWIT660
GTAGWIYKNV  QELLLGIIPD  YDGIIINPKL  PSHWNKVKIK  RIYQNIIFDI  CIEKTGKERL720
IVDNEIINGN  KIRAINKKYV  KVLYEY746

Enzyme Prediction      help

No EC number prediction in MGYG000004199_00402.

CAZyme Signature Domains help

Created with Snap37741111491862232612983353734104474845225595966346717084738GH94
Family Start End Evalue family coverage
GH94 4 738 2.1e-154 0.7403474903474904

CDD Domains      download full data without filtering help

Created with Snap37741111491862232612983353734104474845225595966346717087732COG3459291677Glyco_hydro_3656252Glyco_transf_3662252GH94N_like_47279GH94N_CBP_like
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3459 COG3459 9.31e-105 7 732 274 1033
Cellobiose phosphorylase [Carbohydrate transport and metabolism].
pfam17167 Glyco_hydro_36 2.09e-87 291 677 7 424
Glycosyl hydrolase 36 superfamily, catalytic domain. This is the catalytic region of the superfamily of enzymes referred to as GH36. UniProtKB:Q76IQ9 is a chitobiose phosphorylase that catalyzes the reversible phosphorolysis of chitobiose into alpha-GlcNAc-1-phosphate and GlcNAc with inversion of the anomeric configuration. The full-length enzyme comprises a beta sandwich domain and an (alpha/alpha)(6) barrel domain. The alpha-helical barrel component of the domain, this family, is the catalytic region.
pfam06165 Glyco_transf_36 4.59e-25 56 252 39 245
Glycosyltransferase family 36. The glycosyltransferase family 36 includes cellobiose phosphorylase (EC:2.4.1.20), cellodextrin phosphorylase (EC:2.4.1.49), chitobiose phosphorylase (EC:2.4.1.-). Many members of this family contain two copies of this domain.
cd11751 GH94N_like_4 3.69e-21 62 252 8 214
Glycoside hydrolase family 94 N-terminal-like domain of uncharacterized function. The glycoside hydrolase family 94 (previously known as glycosyltransferase family 36) includes cellobiose phosphorylase (EC:2.4.1.20), cellodextrin phosphorylase (EC:2.4.1.49), chitobiose phosphorylase (EC:2.4.1.-), amongst other members. Their N-terminal domain is involved in oligomerization and may play a role in catalysis, but it is separate from the catalytic domain [an (alpha/alpha)(6) barrel]. The GH64N domain, as represented by this model, is found near the N-terminus of GH94 members and related proteins with uncharacterized specificities.
cd11754 GH94N_CBP_like 1.21e-19 7 279 4 287
N-terminal domain of cellobiose phosphorylase (CBP) and similar proteins. The glycoside hydrolase family 94 (previously known as glycosyltransferase family 36) includes cellobiose phosphorylase (EC:2.4.1.20) or cellobiose:phosphate alpha-D-glucosyltransferase, or CepA. This N-terminal domain is involved in oligomerization and may play a role in catalysis, but it is separate from the catalytic domain [an (alpha/alpha)(6) barrel]. Cellobiose phosphorylase participates in the degradation of cellulose, it catalyzes the phosphate dependent hydrolysis of cellobiose into alpha-D-glucose-1-phosphate and D-glucose, a reversible reaction.

CAZyme Hits      help

Created with Snap37741111491862232612983353734104474845225595966346717087730AIQ60507.1|GH947745ACL70723.1|GH947738AZO94981.1|GH947741AOT69310.1|GH947743APF19318.1|GH94
Hit ID E-Value Query Start Query End Hit Start Hit End
AIQ60507.1 2.58e-107 7 730 5 751
ACL70723.1 2.11e-97 7 745 4 774
AZO94981.1 2.46e-91 7 738 4 775
AOT69310.1 1.16e-90 7 741 4 804
APF19318.1 2.83e-90 7 743 5 792

PDB Hits      download full data without filtering help

Created with Snap377411114918622326129833537341044748452255959663467170877363QDE_A77323RRS_A77323S4C_A77322CQS_A77323ACT_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3QDE_A 4.26e-83 7 736 4 799
ChainA, Cellobiose phosphorylase [Acetivibrio thermocellus],3QDE_B Chain B, Cellobiose phosphorylase [Acetivibrio thermocellus]
3RRS_A 4.01e-69 7 732 4 807
Crystalstructure analysis of cellobiose phosphorylase from Cellulomonas uda [Cellulomonas uda],3RRS_B Crystal structure analysis of cellobiose phosphorylase from Cellulomonas uda [Cellulomonas uda],3RSY_A Cellobiose phosphorylase from Cellulomonas uda in complex with sulfate and glycerol [Cellulomonas uda],3RSY_B Cellobiose phosphorylase from Cellulomonas uda in complex with sulfate and glycerol [Cellulomonas uda],3S4A_A Cellobiose phosphorylase from Cellulomonas uda in complex with cellobiose [Cellulomonas uda],3S4A_B Cellobiose phosphorylase from Cellulomonas uda in complex with cellobiose [Cellulomonas uda],3S4B_A Cellobiose phosphorylase from Cellulomonas uda in complex with glucose [Cellulomonas uda],3S4B_B Cellobiose phosphorylase from Cellulomonas uda in complex with glucose [Cellulomonas uda]
3S4C_A 4.01e-69 7 732 4 807
Lactosephosphorylase in complex with sulfate [Cellulomonas uda],3S4D_A Lactose phosphorylase in a ternary complex with cellobiose and sulfate [Cellulomonas uda]
2CQS_A 7.28e-69 7 732 24 827
CrystalStructure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Ammonium Sulfate [Cellulomonas gilvus],2CQS_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Ammonium Sulfate [Cellulomonas gilvus],2CQT_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Sodium/Potassium Phosphate [Cellulomonas gilvus],2CQT_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Sodium/Potassium Phosphate [Cellulomonas gilvus],3QFY_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and Isofagomine [Cellulomonas gilvus],3QFY_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and Isofagomine [Cellulomonas gilvus],3QFZ_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and 1-Deoxynojirimycin [Cellulomonas gilvus],3QFZ_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Sulfate and 1-Deoxynojirimycin [Cellulomonas gilvus],3QG0_A Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Phosphate and 1-Deoxynojirimycin [Cellulomonas gilvus],3QG0_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Complexed with Phosphate and 1-Deoxynojirimycin [Cellulomonas gilvus]
3ACT_A 6.72e-68 7 732 24 827
CrystalStructure of Cellvibrio gilvus Cellobiose Phosphorylase Histidine mutant [Cellulomonas gilvus ATCC 13127],3ACT_B Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Histidine mutant [Cellulomonas gilvus ATCC 13127]

Swiss-Prot Hits      download full data without filtering help

Created with Snap37741111491862232612983353734104474845225595966346717087736sp|B9K7M6|CBPA_THENN7736sp|Q9F8X1|CHBP_VIBFU7734sp|Q76IQ9|CHBP_VIBPR16732sp|Q7S0S2|CELAP_NEUCR64722sp|Q8P3J4|CELAP_XANCP
Hit ID E-Value Query Start Query End Hit Start Hit End Description
B9K7M6 9.17e-90 7 736 4 801
Cellobiose phosphorylase OS=Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) OX=309803 GN=cbpA PE=1 SV=1
Q9F8X1 3.41e-70 7 736 4 785
N,N'-diacetylchitobiose phosphorylase OS=Vibrio furnissii OX=29494 GN=chbP PE=1 SV=1
Q76IQ9 1.51e-63 7 734 4 783
N,N'-diacetylchitobiose phosphorylase OS=Vibrio proteolyticus OX=671 GN=chbP PE=1 SV=1
Q7S0S2 1.21e-59 16 732 18 769
Cellobionic acid phosphorylase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=NCU09425 PE=1 SV=1
Q8P3J4 5.59e-58 64 722 91 769
Cellobionic acid phosphorylase OS=Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=XCC4077 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004199_00402.