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CAZyme Information: MGYG000004132_01450

You are here: Home > Sequence: MGYG000004132_01450

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species V9D3004 sp900760345
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; V9D3004; V9D3004 sp900760345
CAZyme ID MGYG000004132_01450
CAZy Family GH8
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
636 70370.15 8.7927
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004132 2510246 MAG United Kingdom Europe
Gene Location Start: 42663;  End: 44573  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.8 3.2.1.4 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH8 303 614 2e-82 0.9375

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3405 BcsZ 5.95e-50 251 626 1 355
Endo-1,4-beta-D-glucanase Y [Carbohydrate transport and metabolism].
pfam01270 Glyco_hydro_8 2.40e-24 305 613 25 317
Glycosyl hydrolases family 8.
NF033186 internalin_K 5.66e-07 58 248 396 541
class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.
pfam03154 Atrophin-1 8.06e-07 24 247 52 273
Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
PHA03247 PHA03247 2.69e-06 118 256 2715 2859
large tegument protein UL36; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUL54973.1 1.93e-161 247 626 166 544
QNU67295.1 1.12e-160 249 622 29 406
ADL50930.1 1.45e-147 251 629 32 413
BAV13036.1 2.16e-147 251 629 44 425
AEY65232.1 1.13e-145 249 629 26 410

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6SUD_A 1.32e-115 250 622 6 380
Structureof L320A mutant of Rex8A from Paenibacillus barcinonensis complexed with xylose. [Paenibacillus barcinonensis],6SUD_B Structure of L320A mutant of Rex8A from Paenibacillus barcinonensis complexed with xylose. [Paenibacillus barcinonensis]
6SRD_A 1.86e-115 250 622 6 380
Structureof Rex8A from Paenibacillus barcinonensis complexed with xylose. [Paenibacillus barcinonensis],6SRD_B Structure of Rex8A from Paenibacillus barcinonensis complexed with xylose. [Paenibacillus barcinonensis]
6G00_A 1.29e-114 249 626 3 398
CrystalStructure of a GH8 xylanase from Teredinibacter turnerae [Teredinibacter turnerae T7901],6G09_A Crystal Structure of a GH8 xylobiose complex from Teredinibacter turnerae [Teredinibacter turnerae T7901],6G0B_A Crystal Structure of a GH8 xylotriose complex from Teredinibacter Turnerae [Teredinibacter turnerae T7901]
6SHY_A 1.47e-114 250 622 6 380
Structureof L320A/H321S double mutant of Rex8A from Paenibacillus barcinonensis [Paenibacillus barcinonensis],6SHY_B Structure of L320A/H321S double mutant of Rex8A from Paenibacillus barcinonensis [Paenibacillus barcinonensis]
6TPP_A 1.47e-114 250 622 6 380
Structureof E70A mutant of Rex8A from Paenibacillus barcinonensis. [Paenibacillus barcinonensis],6TPP_B Structure of E70A mutant of Rex8A from Paenibacillus barcinonensis. [Paenibacillus barcinonensis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A0A0S2UQQ5 9.52e-115 250 622 6 380
Reducing-end xylose-releasing exo-oligoxylanase Rex8A OS=Paenibacillus barcinonensis OX=198119 GN=rex8A PE=1 SV=1
Q9KB30 5.03e-104 250 626 6 383
Reducing end xylose-releasing exo-oligoxylanase OS=Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) OX=272558 GN=BH2105 PE=1 SV=1
A1A048 3.60e-71 260 620 14 377
Reducing end xylose-releasing exo-oligoxylanase OS=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) OX=367928 GN=xylA PE=1 SV=1
P37701 7.41e-34 265 634 52 404
Endoglucanase 2 OS=Ruminiclostridium josui OX=1499 GN=celB PE=3 SV=1
P37699 2.13e-32 254 634 40 404
Endoglucanase C OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=celCCC PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000229 0.999181 0.000159 0.000152 0.000140 0.000129

TMHMM  Annotations      download full data without filtering help

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