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CAZyme Information: MGYG000004017_02080
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | HGM11588 sp900754755 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; HGM11588; HGM11588 sp900754755 | |||||||||||
| CAZyme ID | MGYG000004017_02080 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7854; End: 11654 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 858 | 1074 | 1.7e-54 | 0.9147982062780269 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 1.74e-25 | 1085 | 1262 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 2.80e-22 | 863 | 1266 | 50 | 695 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 7.43e-15 | 856 | 1031 | 16 | 204 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG5542 | COG5542 | 5.15e-14 | 300 | 605 | 90 | 386 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG4346 | COG4346 | 3.31e-11 | 882 | 1211 | 132 | 405 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ASA25569.1 | 5.17e-238 | 25 | 1261 | 28 | 1263 |
| QUC68008.1 | 5.59e-235 | 2 | 1265 | 5 | 1423 |
| AIQ27397.1 | 2.77e-233 | 25 | 1261 | 28 | 1274 |
| AIQ39188.1 | 1.18e-231 | 25 | 1261 | 28 | 1274 |
| QTE75201.1 | 1.39e-231 | 2 | 1265 | 5 | 1423 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 4.13e-26 | 863 | 1253 | 67 | 504 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| P9WN04 | 5.76e-23 | 863 | 1253 | 73 | 510 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 5.76e-23 | 863 | 1253 | 73 | 510 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 1.01e-22 | 886 | 1261 | 99 | 516 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000204 | 0.999177 | 0.000158 | 0.000154 | 0.000138 | 0.000131 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 5 | 23 |
| 216 | 233 |
| 253 | 275 |
| 331 | 353 |
| 365 | 387 |
| 423 | 440 |
| 447 | 469 |
| 515 | 537 |
| 544 | 563 |
| 567 | 582 |
| 587 | 606 |
| 621 | 643 |
| 683 | 702 |
| 905 | 927 |
| 961 | 983 |
| 1009 | 1028 |
| 1049 | 1071 |
| 1144 | 1163 |
| 1170 | 1188 |
| 1193 | 1212 |
| 1225 | 1244 |