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CAZyme Information: MGYG000003997_00508

You are here: Home > Sequence: MGYG000003997_00508

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species HGM12650 sp900761725
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; HGM12650; HGM12650 sp900761725
CAZyme ID MGYG000003997_00508
CAZy Family GH18
CAZyme Description Spore germination protein YaaH
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
462 51480.63 4.79
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003997 1773221 MAG United Kingdom Europe
Gene Location Start: 109925;  End: 111313  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003997_00508.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 205 440 7.2e-27 0.7027027027027027

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 2.11e-84 141 451 4 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 5.11e-81 34 455 1 422
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
cd06549 GH18_trifunctional 4.42e-26 186 448 53 298
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.
pfam00704 Glyco_hydro_18 9.06e-14 204 440 74 304
Glycosyl hydrolases family 18.
smart00636 Glyco_18 3.98e-13 198 440 69 331
Glyco_18 domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CAB1246914.1 9.36e-114 34 460 1 426
AOZ77090.1 2.18e-111 34 461 1 426
AOZ80887.1 2.18e-111 34 461 1 426
AJA53944.1 2.18e-111 34 461 1 426
QNU67347.1 6.75e-110 34 460 1 425

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4S3K_A 9.46e-62 36 459 6 431
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
4S3J_A 1.83e-60 36 459 5 429
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
3CZ8_A 2.44e-42 129 438 1 306
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4Q6T_A 5.23e-19 168 453 37 337
Thecrystal structure of a class V chitininase from Pseudomonas fluorescens Pf-5 [Pseudomonas protegens Pf-5]
5JH8_A 1.06e-16 164 451 28 310
Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P0DPJ9 6.64e-60 36 459 4 428
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
Q9K3E4 3.78e-58 36 459 4 428
Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1
O05495 1.68e-56 34 460 1 420
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P37531 1.90e-51 34 459 1 427
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
O32258 2.54e-26 147 452 38 340
Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000043 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

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21 39