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CAZyme Information: MGYG000003995_00171

You are here: Home > Sequence: MGYG000003995_00171

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Cyanobacteria; Vampirovibrionia; Gastranaerophilales; Gastranaerophilaceae; Zag111;
CAZyme ID MGYG000003995_00171
CAZy Family GH23
CAZyme Description Membrane-bound lytic murein transglycosylase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
663 MGYG000003995_2|CGC1 76585.33 9.6462
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003995 1806864 MAG United Kingdom Europe
Gene Location Start: 58874;  End: 60865  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003995_00171.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH23 516 656 6.9e-27 0.8962962962962963

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd13401 Slt70-like 2.37e-52 511 657 2 149
70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.
cd16896 LT_Slt70-like 2.90e-44 512 654 1 144
uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd16893 LT_MltC_MltE 4.71e-28 517 654 1 161
membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins. MltC and MltE are periplasmic, outer membrane attached lytic transglycosylases (LTs), which cleave beta-1,4-glycosidic bonds joining N-acetylmuramic acid and N-acetylglucosamine in the cell wall peptidoglycan, yielding 1,6-anhydromuropeptides. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda
cd00254 LT-like 8.27e-28 531 655 2 111
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
COG0741 MltE 2.86e-27 519 661 143 287
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AOR39013.1 2.45e-215 6 661 6 657
AFY32291.1 1.08e-44 204 661 227 710
QMS87397.1 1.67e-43 71 661 121 710
BCU09513.1 2.11e-43 210 661 234 707
ARI81489.1 2.85e-43 210 661 234 707

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6FBT_A 1.59e-22 530 650 464 585
ChainA, Lytic murein transglycosylase [Pseudomonas aeruginosa]
5OHU_A 1.76e-22 530 650 493 614
TheX-ray Structure of Lytic Transglycosylase Slt from Pseudomonas aeruginosa [Pseudomonas aeruginosa]
6FCQ_A 3.75e-22 530 650 464 585
ChainA, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCR_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCS_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCU_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa]
6FC4_A 3.76e-22 530 650 465 586
ChainA, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa]
5MPQ_A 5.10e-19 505 650 406 548
BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O31608 1.10e-17 519 655 64 180
Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1
P0AGC3 6.71e-16 511 657 476 627
Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1
P0AGC4 6.71e-16 511 657 476 627
Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1
O31976 2.77e-15 511 654 1418 1541
SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2
O64046 2.77e-15 511 654 1418 1541
Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.744729 0.244377 0.002905 0.000805 0.000545 0.006648

TMHMM  Annotations      download full data without filtering help

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