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CAZyme Information: MGYG000003985_00864

You are here: Home > Sequence: MGYG000003985_00864

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-873 sp002493945
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-873; CAG-873 sp002493945
CAZyme ID MGYG000003985_00864
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
704 79732.4 5.3901
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003985 2303173 MAG United Kingdom Europe
Gene Location Start: 2435;  End: 4549  Strand: -

Full Sequence      Download help

MNLNRIIISA  LLAATALGAS  AEKVASPSGL  IVVDAYVADG  GKPTYTVEYK  GRPVIKPSHL60
GFELIGATPL  LDKFEITGTE  TASSDQTWTP  VWGENSTIRD  NYNELLVHYK  QPSTDRYMDV120
RFRVYDDGVG  FRYEFPIDGP  LGYFNVKEER  TQFAMTGDHT  AWWIAGDYDT  QEYDYTESRL180
SEIRGLMDSA  ISSNASQTQF  SPTGVQTSLQ  LKTDDGIYIN  IHEAALVDYS  CMHLNLDDRN240
MVFESWLTPD  AQGVKGRLQT  PAKSPWRTLI  ISDDARDMLA  SNLILNLNDP  CAYEDTSWIK300
PVKYVGVWWE  MIAGGKQWSY  TYDLPSVKLD  RLDYTTTKCH  GQHPANNDNV  KRYIDFAAEH360
GFDQVLVEGW  NIGWEDWFGH  QKDYVFDFVT  PYPDFDIDML  NRYAADKGVK  LMMHHETSSA420
ATNYERHMDA  AYQLMKKYGY  NAVKSGYVGN  IIPYGEHHYS  QWMVNHYLYA  LKKAADYGIM480
VNAHEAVRPT  GLCRTYPNLV  GNESARGTEY  EAFAGNKPSH  TTVLPFTRLQ  GGPMDYTPGI540
FEMDVTKINP  QSKGHVNSTL  ARQLALYVTM  YSPLQMAADL  PEHYERFMDA  FQFIKDVPVD600
WQKSIYLEAE  PGQYITAARK  DKNSDEWYVG  CTSGENGHKS  DLRLDFLDKG  RKYEATIYAD660
APDAHYRENP  QAYVISRKKV  DSRTRLKLNA  APGGGYAISI  KPVD704

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap357010514017621124628131635238742245749252856359863366812700GH97
Family Start End Evalue family coverage
GH97 12 700 1.4e-250 0.9904912836767037

CDD Domains      download full data without filtering help

Created with Snap3570105140176211246281316352387422457492528563598633668295598Glyco_hydro_9726290GH97_N601701GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 2.35e-143 295 598 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 9.77e-101 26 290 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 5.70e-43 601 701 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap35701051401762112462813163523874224574925285635986336683703QDO70251.1|GH973703QUT91746.1|GH973700ADY35295.1|GH973703ALJ62516.1|GH973703QUT68067.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
QDO70251.1 0.0 3 703 1 701
QUT91746.1 0.0 3 703 1 701
ADY35295.1 0.0 3 700 1 698
ALJ62516.1 0.0 3 703 1 701
QUT68067.1 0.0 3 703 1 701

PDB Hits      download full data without filtering help

Created with Snap3570105140176211246281316352387422457492528563598633668227032D73_A237032JKA_A227033WFA_A247015HQ4_A247015HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 22 703 23 726
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 23 703 13 715
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 22 703 3 706
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 3.16e-167 24 701 3 659
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 3.16e-167 24 701 3 659
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap357010514017621124628131635238742245749252856359863366822703sp|G8JZS4|SUSB_BACTN25701sp|Q8A6L0|AGAL_BACTN38668sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 22 703 23 726
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 1.11e-64 25 701 26 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 5.32e-34 38 668 54 596
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000289 0.998967 0.000185 0.000189 0.000187 0.000163

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003985_00864.