CAZyme Information: MGYG000003957_01411

Basic Information

• Species: Parabacteroides sp014287585
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides sp014287585
• CAZyme ID: MGYG000003957_01411
• CAZy Family: GH109
• CAZyme Description: Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
465	MGYG000003957_22|CGC1	50711.44	7.4627

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003957	4724401	MAG	United Kingdom	Europe

• Gene Location: Start: 27468; End: 28865 Strand: +

Full Sequence      

MKKENSISRRSFLKSTAMAGALGAIGTGSASVLTSCAGGGAEGSAANKPLKEPGTYYIPE
LPDLATDGKELKAGVIGCGGRGSGAAFNFLNAANGVTIVALGDTFQERVDSLADKLKSEK
NIDIPADKRFVGLDAYQKVIDSGVDVVIIATPPVFRPLHFQYATEKGKHSFLEKPICVDP
VGYRTIMATAKQAQAKNLCVLTGTQRHHQRNYVESYKKIMEGAIGEITGGVVYWNGGKLW
HRDRQPGWNDCEAMIKDWVNWKWLSGDHIVEQHVHNIDVFTWFSGLKPVSAVGFGSRQRR
VTGDQYDNFSIDFTMDNGIHLHSMCRQIDGCVNNVSEFIQGSKGSWSTANGETVIKDNAG
NVIWKFDKEAEKAAHSQTDPYTLEHVNWINCIRGGKPLEQASETAIANMAAIMGRESAYT
GLETTWDAMTASPMDYTPKDLNLGKMDMSGFTVAIPGKAYEPKKK

Enzyme Prediction     

EC	3.2.1.18

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH109	69	228	8.8e-16	0.38596491228070173

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0673	MviM	4.66e-38	68	421	1	335	Predicted dehydrogenase [General function prediction only].
TIGR04380	myo_inos_iolG	2.75e-14	70	421	1	326	inositol 2-dehydrogenase. All members of the seed alignment for this model are known or predicted inositol 2-dehydrogenase sequences co-clustered with other enzymes for catabolism of myo-inositol or closely related compounds. Inositol 2-dehydrogenase catalyzes the first step in inositol catabolism. Members of this family may vary somewhat in their ranges of acceptable substrates and some may act on analogs to myo-inositol rather than myo-inositol per se. [Energy metabolism, Sugars]
pfam01408	GFO_IDH_MocA	5.09e-11	71	196	1	115	Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilize NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot.
pfam10518	TAT_signal	1.10e-04	6	31	1	26	TAT (twin-arginine translocation) pathway signal sequence.
PRK10206	PRK10206	7.97e-04	141	227	62	145	putative oxidoreductase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT51053.1	5.80e-305	1	465	1	461
BBK93797.1	1.03e-300	1	463	1	460
QIX65768.1	1.03e-300	1	463	1	460
QUT96603.1	1.03e-300	1	463	1	460
AST52349.1	1.03e-300	1	463	1	460

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3CEA_A	1.81e-10	66	296	4	210	ChainA, Myo-inositol 2-dehydrogenase [Lactiplantibacillus plantarum WCFS1],3CEA_B Chain B, Myo-inositol 2-dehydrogenase [Lactiplantibacillus plantarum WCFS1],3CEA_C Chain C, Myo-inositol 2-dehydrogenase [Lactiplantibacillus plantarum WCFS1],3CEA_D Chain D, Myo-inositol 2-dehydrogenase [Lactiplantibacillus plantarum WCFS1]
4N54_A	7.50e-07	69	293	13	215	ChainA, Inositol dehydrogenase [Lacticaseibacillus casei BL23],4N54_B Chain B, Inositol dehydrogenase [Lacticaseibacillus casei BL23],4N54_C Chain C, Inositol dehydrogenase [Lacticaseibacillus casei BL23],4N54_D Chain D, Inositol dehydrogenase [Lacticaseibacillus casei BL23]
4MKX_A	7.57e-07	69	293	16	218	ChainA, Inositol dehydrogenase [Lacticaseibacillus casei BL23],4MKZ_A Chain A, Inositol dehydrogenase [Lacticaseibacillus casei BL23]
3EC7_A	7.62e-07	63	282	16	204	CrystalStructure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_B Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_C Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_D Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_E Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_F Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_G Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],3EC7_H Crystal Structure of Putative Dehydrogenase from Salmonella typhimurium LT2 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
3E18_A	1.02e-06	111	319	25	222	CRYSTALSTRUCTURE OF NAD-BINDING PROTEIN FROM Listeria innocua [Listeria innocua],3E18_B CRYSTAL STRUCTURE OF NAD-BINDING PROTEIN FROM Listeria innocua [Listeria innocua]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q9RK81	3.99e-12	1	302	1	269	Glycosyl hydrolase family 109 protein OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) OX=100226 GN=SCO0529 PE=3 SV=1
A9N564	3.87e-06	71	282	3	183	Inositol 2-dehydrogenase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) OX=1016998 GN=iolG PE=3 SV=1
B5F3F4	3.87e-06	71	282	3	183	Inositol 2-dehydrogenase OS=Salmonella agona (strain SL483) OX=454166 GN=iolG PE=3 SV=1
Q8ZK57	3.87e-06	71	282	3	183	Inositol 2-dehydrogenase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=iolG PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as TATLIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000000	0.000000	0.000000	0.005053	0.994952	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003957_01411.