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CAZyme Information: MGYG000003927_00263
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminiclostridium_E; | |||||||||||
| CAZyme ID | MGYG000003927_00263 | |||||||||||
| CAZy Family | GH27 | |||||||||||
| CAZyme Description | Alpha-galactosidase A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 115062; End: 116252 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH27 | 105 | 370 | 1.3e-71 | 0.982532751091703 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd14792 | GH27 | 5.75e-141 | 9 | 298 | 1 | 271 | glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. |
| PLN02808 | PLN02808 | 1.93e-115 | 5 | 390 | 28 | 382 | alpha-galactosidase |
| PLN02229 | PLN02229 | 1.54e-107 | 5 | 389 | 59 | 415 | alpha-galactosidase |
| PLN02692 | PLN02692 | 6.32e-103 | 5 | 392 | 52 | 409 | alpha-galactosidase |
| pfam16499 | Melibiase_2 | 1.76e-92 | 8 | 298 | 1 | 284 | Alpha galactosidase A. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CBL33680.1 | 3.07e-316 | 1 | 396 | 1 | 396 |
| CBK97479.1 | 5.11e-315 | 1 | 396 | 1 | 396 |
| ADU22068.1 | 2.38e-212 | 1 | 396 | 1 | 385 |
| APC40140.1 | 5.17e-205 | 1 | 395 | 1 | 387 |
| QAA34453.1 | 6.73e-205 | 4 | 395 | 1 | 374 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UAS_A | 1.37e-96 | 2 | 389 | 2 | 357 | ChainA, alpha-galactosidase [Oryza sativa] |
| 6F4C_B | 9.05e-95 | 5 | 389 | 5 | 358 | Nicotianabenthamiana alpha-galactosidase [Nicotiana benthamiana] |
| 4NZJ_A | 1.80e-84 | 2 | 389 | 94 | 471 | Crystalstructure of a putative alpha-galactosidase (BF1418) from Bacteroides fragilis NCTC 9343 at 1.57 A resolution [Bacteroides fragilis NCTC 9343] |
| 4OGZ_A | 2.51e-83 | 2 | 392 | 94 | 473 | Crystalstructure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343],4OGZ_B Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343] |
| 3A5V_A | 1.45e-81 | 5 | 384 | 5 | 383 | Crystalstructure of alpha-galactosidase I from Mortierella vinacea [Umbelopsis vinacea] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P14749 | 1.19e-98 | 2 | 389 | 49 | 405 | Alpha-galactosidase OS=Cyamopsis tetragonoloba OX=3832 PE=1 SV=1 |
| Q8VXZ7 | 3.33e-96 | 5 | 389 | 69 | 425 | Alpha-galactosidase 3 OS=Arabidopsis thaliana OX=3702 GN=AGAL3 PE=1 SV=1 |
| Q9FXT4 | 4.10e-95 | 2 | 389 | 57 | 412 | Alpha-galactosidase OS=Oryza sativa subsp. japonica OX=39947 GN=Os10g0493600 PE=1 SV=1 |
| Q8RX86 | 6.11e-95 | 1 | 390 | 32 | 390 | Alpha-galactosidase 2 OS=Arabidopsis thaliana OX=3702 GN=AGAL2 PE=1 SV=1 |
| Q42656 | 6.32e-93 | 5 | 389 | 20 | 373 | Alpha-galactosidase OS=Coffea arabica OX=13443 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000057 | 0.000026 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |