dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000003546_01670

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Basic Information help

Species

UBA1181 sp900769555

Lineage

Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Paludibacteraceae; UBA1181; UBA1181 sp900769555

CAZyme ID

MGYG000003546_01670

CAZy Family

CE6

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
854	MGYG000003546_128\|CGC2	94180.19	4.3752

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003546	3032937	MAG	Fiji	Oceania

Gene Location

Start: 33599; End: 36163 Strand: +

Full Sequence Download help

Enzyme Prediction help

EC	3.1.1.72

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
CBM6	657	786	2.9e-34	0.9782608695652174
CE6	91	202	1.2e-31	0.98989898989899
CE1	316	478	5.9e-26	0.6035242290748899

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04080	CBM6_cellulase-like	1.23e-46	651	787	1	144	Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase). This family includes carbohydrate binding module 6 (CBM6) domains that are appended to several glycoside hydrolase (GH) domains, including GH5 (cellulase) and GH16, as well as to coagulation factor 5/8 carbohydrate-binding domains. CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. The CBM6s are appended to GHs that display a diversity of substrate specificities. For some members of this family information is available about the specific substrates of the appended GH domains. It includes the CBM domains of various enzymes involved in cell wall degradation including, an extracellular beta-1,3-glucanase from Lysobacter enzymogenes encoded by the gluC gene (its catalytic domain belongs to the GH16 family), the tandem CBM domains of Pseudomonas sp. PE2 beta-1,3(4)-glucanase A (its catalytic domain also belongs to GH16), and a family 6 CBM from Cellvibrio mixtus Endoglucanase 5A (CmCBM6) which binds to the beta1,4-beta1,3-mixed linked glucans lichenan, and barley beta-glucan, cello-oligosaccharides, insoluble forms of cellulose, the beta1,3-glucan laminarin, and xylooligosaccharides, and the CBM6 of Fibrobacter succinogenes S85 XynD xylanase, appended to a GH10 domain, and Cellvibrio japonicas Cel5G appended to a GH5 (cellulase) domain. GH5 (cellulase) family includes enzymes with several known activities such as endoglucanase, beta-mannanase, and xylanase, which are involved in the degradation of cellulose and xylans. GH16 family includes enzymes with lichenase, xyloglucan endotransglycosylase (XET), and beta-agarase activities. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. For CmCBM6 it has been shown that these two binding sites have different ligand specificities.
COG3509	LpqC	1.78e-34	317	543	46	307	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport and catabolism].
pfam03629	SASA	4.29e-28	29	273	1	226	Carbohydrate esterase, sialic acid-specific acetylesterase. The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.
smart00606	CBD_IV	6.29e-24	648	786	1	129	Cellulose Binding Domain Type IV.
pfam03422	CBM_6	1.97e-20	656	784	1	118	Carbohydrate binding module (family 6).

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADQ79784.1	6.62e-98	2	275	3	275
QDK78717.1	7.24e-95	10	279	6	279
AOZ99799.1	2.53e-94	12	275	11	275
AKD53829.1	1.15e-93	24	281	22	283
AUD03642.1	4.15e-93	2	275	4	275

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2Y8K_A	3.09e-18	654	760	342	455	ChainA, Carbohydrate Binding Family 6 [Acetivibrio thermocellus],5LA0_A Chain A, Carbohydrate binding family 6 [Acetivibrio thermocellus JW20],5LA1_A Chain A, Carbohydrate binding family 6 [Acetivibrio thermocellus JW20]
5LA2_A	3.09e-18	654	760	342	455	ChainA, Carbohydrate binding family 6 [Acetivibrio thermocellus],5LA2_B Chain B, Carbohydrate binding family 6 [Acetivibrio thermocellus]
5G56_A	4.15e-18	654	801	340	495	ChainA, Carbohydrate Binding Family 6 [Acetivibrio thermocellus]
3WYD_A	6.27e-15	319	481	24	184	C-terminalesterase domain of LC-Est1 [uncultured organism],3WYD_B C-terminal esterase domain of LC-Est1 [uncultured organism]
5X6S_A	7.11e-12	316	449	15	155	Acetylxylan esterase from Aspergillus awamori [Aspergillus awamori],5X6S_B Acetyl xylan esterase from Aspergillus awamori [Aspergillus awamori]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
D5EXZ4	1.30e-67	26	279	42	299	Carbohydrate acetyl esterase/feruloyl esterase OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23) OX=264731 GN=axe1-6A PE=1 SV=1
B8YG19	6.54e-55	316	581	56	306	Bifunctional acetylxylan esterase/xylanase XynS20E OS=Neocallimastix patriciarum OX=4758 GN=xynS20E PE=1 SV=1
Q9Y871	3.68e-17	318	545	292	535	Feruloyl esterase B OS=Piromyces equi OX=99929 GN=ESTA PE=2 SV=1
P52090	1.31e-14	317	496	50	267	Poly(3-hydroxyalkanoate) depolymerase C OS=Paucimonas lemoignei OX=29443 GN=phaZ1 PE=3 SV=1
A1CC33	1.92e-12	354	519	86	247	Probable feruloyl esterase C OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=faeC-2 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000763	0.998454	0.000197	0.000190	0.000172	0.000184

TMHMM Annotations download full data without filtering help

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