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CAZyme Information: MGYG000003512_01212
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UBA11524 sp900769075 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; UBA11524; UBA11524 sp900769075 | |||||||||||
| CAZyme ID | MGYG000003512_01212 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 53954; End: 58219 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 944 | 1177 | 6.4e-54 | 0.9192825112107623 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1928 | PMT1 | 1.97e-20 | 944 | 1177 | 46 | 268 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 1.85e-17 | 941 | 1177 | 16 | 241 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| pfam16192 | PMT_4TMC | 1.59e-15 | 1201 | 1369 | 8 | 179 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| pfam13231 | PMT_2 | 6.10e-12 | 971 | 1115 | 2 | 137 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| COG5542 | COG5542 | 7.11e-10 | 307 | 668 | 86 | 383 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTE68569.1 | 0.0 | 29 | 1382 | 35 | 1392 |
| QUA53848.1 | 0.0 | 26 | 1382 | 28 | 1362 |
| QTE75201.1 | 0.0 | 9 | 1382 | 5 | 1412 |
| QTE71236.1 | 0.0 | 23 | 1382 | 6 | 1397 |
| QUC68008.1 | 0.0 | 9 | 1382 | 5 | 1412 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 2.47e-18 | 948 | 1373 | 73 | 504 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 2.47e-18 | 948 | 1373 | 73 | 504 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 9.81e-18 | 938 | 1399 | 57 | 505 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| Q2LZ62 | 4.94e-06 | 948 | 1177 | 223 | 440 | Protein O-mannosyltransferase 1 OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=rt PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as LIPO
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.001308 | 0.445547 | 0.552306 | 0.000432 | 0.000213 | 0.000178 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 218 | 237 |
| 258 | 280 |
| 321 | 343 |
| 390 | 412 |
| 427 | 449 |
| 469 | 488 |
| 531 | 553 |
| 574 | 596 |
| 611 | 630 |
| 656 | 675 |
| 695 | 714 |
| 757 | 779 |
| 990 | 1012 |
| 1041 | 1063 |
| 1090 | 1112 |
| 1151 | 1173 |
| 1245 | 1267 |
| 1295 | 1314 |
| 1319 | 1341 |
| 1353 | 1375 |