CAZyme Information: MGYG000003489_00404

Basic Information

• Species: Prevotellamassilia sp900768625
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotellamassilia; Prevotellamassilia sp900768625
• CAZyme ID: MGYG000003489_00404
• CAZy Family: GH33
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
993		107926.85	5.4315

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003489	2843857	MAG	Fiji	Oceania

• Gene Location: Start: 1474; End: 4455 Strand: -

Full Sequence      

MINTTRLSALALGLAFAAGSWADVPFKVTKVTADGKFDPSTVWYTMTIGTGNIRISNNKG
ADFISLTGKLSPADENLWCFVGDEANGYQIYNKETGTSMVLTAPVDMSESEGGTAYAVLK
DATLTDAAYSNRWDFKEAKMTSGNQSISVENGWYVNQHSLTANILNNRQGKLAFWSAGFD
NGSAIVVSEAGKTFEVNMANGKFTATNPEGTYASAWASTATDPTLRLTTGANNMSKHGDS
DFNLASGGTKSSTYNLTAGSGYLVTGYSFTFQNEKANANALKFVVGDKEYNVTNEPQTIT
VSNLTEATAQFTLTGDNHNVTVTNFTVDVCVSFAAGEKQTDLFVTDGSKPAPYRIPAIAK
AHNGDLIAVSDYRPCGSDIGYGRVDLMGRISKDNGQTWGEEFVIKSGTGTKGAIDCGFGD
AALVADSESDEVLLISVCGNTPYPNATRSNPNPVARFRSHDNGKTWSDFENITESIYTLF
DDSKLGAVNGLFFGSGRICQSRLVKVGKYYRLYAALTARPNGNRVIYSDDFGETWHALGC
LTVSPAPAGDEPKCEELPDGTVILSSRMNGGRFYNLFTYTDVEKAEGSWGTVATSNADNK
GTIATGNSTNGEILIIPAIRNKDKAEVYVALQSVPFGSGRANVGIYYKELSSPDDVKSPA
AFAANWDGKHQASKLGSAYSTMIMQANDSIAFFYEEETYGRAYTNVYKQYSLEGLTGGAY
TYNKHQSPASFVKKQLERKLEAATKDLEYGIAVGEMDKSRQSATEQQFKQLVADYVNNPT
PQEYIDAQKRITETIENGRVQVVNGHAYTLLNKQRTGKYLNPSETVNTKEGKITFGGADA
DYESARQQFVFESTGKDGEWYILNKATQTYLSATKATTKLFVTQETDKANAGTYVVKPYK
QGWSNVVCTNPAVTNYIALNLNANFQLIQSTATPDAARWRVVPAEYFVEGIGEVETTTEQ
KEVTLYDLQGRVIKRAPRTGVYISSDHRKHVAH

Enzyme Prediction     

No EC number prediction in MGYG000003489_00404.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH33	346	701	4.5e-44	0.9269005847953217

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd15482	Sialidase_non-viral	2.33e-60	340	711	1	339	Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
COG4409	NanH	3.01e-04	331	482	251	425	Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QFQ12979.1	4.28e-111	329	721	11	398
QUB76590.1	1.64e-110	25	983	57	1044
QUB85277.1	2.20e-110	25	971	38	1011
ALO48969.1	3.08e-110	329	724	16	403
QYR10380.1	9.75e-109	322	720	10	395

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7LBU_A	2.29e-17	341	697	82	415	ChainA, Exo-alpha-sialidase [Cutibacterium acnes],7LBV_A Chain A, Exo-alpha-sialidase [Cutibacterium acnes]
1EUR_A	6.17e-16	339	705	11	353	Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens]
1EUT_A	2.09e-15	339	705	11	353	Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens]
1WCQ_A	6.27e-15	339	705	7	349	Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens]
1W8N_A	1.09e-14	339	705	7	349	Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q02834	1.24e-14	339	705	53	395	Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
P31206	1.91e-06	351	571	201	419	Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000286	0.999034	0.000174	0.000184	0.000169	0.000151

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003489_00404.