You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000003284_01178
You are here: Home > Sequence: MGYG000003284_01178
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-269 sp900555615 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-269; CAG-269 sp900555615 | |||||||||||
| CAZyme ID | MGYG000003284_01178 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | Surfactin synthase subunit 1 | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 125505; End: 132914 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12467 | PRK12467 | 0.0 | 4 | 2059 | 52 | 2160 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 0.0 | 7 | 2059 | 681 | 2772 | peptide synthase; Validated |
| PRK12316 | PRK12316 | 0.0 | 68 | 2059 | 1624 | 3619 | peptide synthase; Provisional |
| PRK12316 | PRK12316 | 1.38e-179 | 1040 | 2059 | 43 | 1081 | peptide synthase; Provisional |
| cd05930 | A_NRPS | 3.65e-160 | 468 | 940 | 1 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 4.20e-220 | 240 | 2055 | 796 | 2655 |
| BAY90071.1 | 2.01e-140 | 906 | 2036 | 2068 | 3256 |
| BAY30132.1 | 3.21e-139 | 938 | 2036 | 2128 | 3267 |
| ACX49739.1 | 6.79e-124 | 4 | 1767 | 12 | 1847 |
| AFZ04852.1 | 1.71e-117 | 1239 | 2059 | 335 | 1180 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6MFZ_A | 1.65e-239 | 456 | 2059 | 207 | 1794 | Crystalstructure of dimodular LgrA in a condensation state [Brevibacillus parabrevis],6MFZ_B Crystal structure of dimodular LgrA in a condensation state [Brevibacillus parabrevis] |
| 6MFY_A | 3.88e-227 | 456 | 1982 | 207 | 1714 | Crystalstructure of a 5-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis],6MG0_A Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis],6MG0_B Crystal structure of a 5-domain construct of LgrA in the thiolation state [Brevibacillus parabrevis] |
| 5U89_A | 4.10e-144 | 434 | 1477 | 5 | 1071 | Crystalstructure of a cross-module fragment from the dimodular NRPS DhbF [Geobacillus sp. Y4.1MC1] |
| 6MFW_A | 1.13e-139 | 456 | 1472 | 207 | 1205 | Crystalstructure of a 4-domain construct of LgrA in the substrate donation state [Brevibacillus parabrevis] |
| 6MFX_A | 6.94e-139 | 456 | 1472 | 207 | 1205 | Crystalstructure of a 4-domain construct of a mutant of LgrA in the substrate donation state [Brevibacillus parabrevis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P39845 | 0.0 | 3 | 2058 | 7 | 2073 | Plipastatin synthase subunit A OS=Bacillus subtilis (strain 168) OX=224308 GN=ppsA PE=1 SV=2 |
| P0C064 | 0.0 | 4 | 2060 | 2099 | 4158 | Gramicidin S synthase 2 OS=Brevibacillus brevis OX=1393 GN=grsB PE=1 SV=2 |
| P27206 | 0.0 | 4 | 2060 | 8 | 2079 | Surfactin synthase subunit 1 OS=Bacillus subtilis (strain 168) OX=224308 GN=srfAA PE=1 SV=4 |
| O30409 | 0.0 | 4 | 2059 | 3133 | 5187 | Tyrocidine synthase 3 OS=Brevibacillus parabrevis OX=54914 GN=tycC PE=1 SV=1 |
| P94459 | 0.0 | 4 | 2059 | 1059 | 3101 | Plipastatin synthase subunit D OS=Bacillus subtilis (strain 168) OX=224308 GN=ppsD PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000054 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
