CAZyme Information: MGYG000003237_03266

Basic Information

• Species: Victivallis sp002998355
• Lineage: Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; Victivallaceae; Victivallis; Victivallis sp002998355
• CAZyme ID: MGYG000003237_03266
• CAZy Family: GH2
• CAZyme Description: Exo-beta-D-glucosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
822	MGYG000003237_86|CGC1	93592.58	6.2554

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003237	4618450	MAG	United States	North America

• Gene Location: Start: 16995; End: 19463 Strand: +

Full Sequence      

MGSMIDLGGSWTLGCPEWNGRTIAAELPGDNYSALLAAGMIPDPYFGRNEELVQEFRRYE
WEFTREFEVPEELLSRRYVYLNCEMFDTFATVWINGKKAVSTENMFACWRPEVKALLKPG
VNTIRIRFKSSELEAKKAAAGMPFPIPMNSCSKVENLNLIRKPHCHGGWDWGITLMAAGV
YAPLTLTGVDGGRIDAVWTEQKHEKNLVECTAVAELHAEEPCRTAVTFRFNGEEKTVNAS
LKAGRNLVRAKFEVKNPRLWWPNGSGAQELYPLTVETADRTVERMIGLRIIEVVNRPDEY
GVSMFFRVNGVDVFAKGANWIPADAFPSRQTEARYEDLLESARLANMNMIRVWGGGQYEK
DIFYEICDRKGLMVWQDMMFSCSLYPSTEAFIANVMNELDYQIPRLKHHASLAIWCGDNE
VIGATKWYDKERVSTYLVNYDRLNRELWRRVEALDPERMFWPSSPCGGPNNFNDGWHDDS
CGDMHYWEVWHGAKDFSAYYSVRPRFCSEFGYQSFPSFETVASFCPPDQFNVFSPVMDHH
QKCVRGNAPIIGMFGKYFRMPESFGDFLYLSQVQQALAIKTGVEFWRTLKPRCMGTIFWQ
LNDNWPVASWASIEYGGKWKQLQYHAKRFYAPVIATACRDPQDGQTRIFAVSDLRERCKV
TVTAVVSDFDGLPQKRFEFSASLKPGESRCLKAFKPAELAGFNPEEHFMELRLSAECADG
TALSFENTFFFDVFKHCAFRHADVKTAVKAGKDGGFEVTLSTDRPAFFVTLDTPGIPGIF
SDNSLTLLPGEPKTLVFSPKKETTAAELGKALEVNYLRKTYN

Enzyme Prediction     

No EC number prediction in MGYG000003237_03266.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	5	714	1.2e-92	0.7167553191489362

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	6.01e-107	1	816	9	797	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam17753	Ig_mannosidase	8.93e-22	742	814	2	73	Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.
pfam17786	Mannosidase_ig	4.07e-12	644	736	1	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
pfam18368	Ig_GlcNase	8.92e-08	742	798	21	85	Exo-beta-D-glucosaminidase Ig-fold domain. This domain can be found in 2 glycoside hydrolase subfamily of beta-glucosaminidases (EC:3.2.1.165) such as CsxA, from Amycolatopsis orientalis that has exo-beta-D-glucosaminidase (exo-chitosanase) activity. It has an immunoglobulin-like topology.
pfam00703	Glyco_hydro_2	4.65e-06	193	289	2	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AVM44113.1	0.0	1	822	1	822
QDU34180.1	4.85e-270	3	821	9	835
QQE12237.1	2.08e-267	4	821	10	829
ADN01224.1	1.21e-234	5	821	4	808
AYV24530.1	5.83e-234	5	792	4	778

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2VJX_A	9.57e-156	4	821	10	838	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	1.01e-155	4	821	12	840	Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A	1.04e-155	4	821	12	840	ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	2.74e-155	4	821	10	838	Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
2VQU_A	1.14e-153	4	821	10	838	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQU_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q95327	9.84e-120	5	821	23	879	Beta-mannosidase OS=Capra hircus OX=9925 GN=MANBA PE=1 SV=1
Q4FZV0	3.95e-119	2	821	20	881	Beta-mannosidase OS=Rattus norvegicus OX=10116 GN=Manba PE=2 SV=1
O00462	1.44e-118	7	821	25	879	Beta-mannosidase OS=Homo sapiens OX=9606 GN=MANBA PE=1 SV=3
Q29444	8.07e-117	5	821	23	879	Beta-mannosidase OS=Bos taurus OX=9913 GN=MANBA PE=1 SV=1
Q8K2I4	1.85e-112	2	821	20	879	Beta-mannosidase OS=Mus musculus OX=10090 GN=Manba PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000076	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003237_03266.