CAZyme Information: MGYG000002886_01428

Basic Information

• Species: Stenotrophomonas maltophilia
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; Xanthomonadaceae; Stenotrophomonas; Stenotrophomonas maltophilia
• CAZyme ID: MGYG000002886_01428
• CAZy Family: GT51
• CAZyme Description: Penicillin-binding protein 1C

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
643		69970.46	8.4522

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002886	4276654	MAG	United States	North America

• Gene Location: Start: 3353; End: 5284 Strand: -

Full Sequence      

MLRAVQLEVHLSKQQILALYLERAPYGGTIEGVEAASWAYLGKPAAQLSHAEAALLAVLP
QAPSRLRPDRHPEAAQKARDKVLSRMAELGAWTAEEVEDARIENVVARSLRPPLHAALLA
QRLHSAHPGQARIQSSIDIGLQRTLEERVASYFSTLPERTSAALLVVDNQTLQARAYVGT
LAFGDRQRLGHVDMVQAWRSPGSTLKPFLYAMALDDGLIHSESLLVDAPQSFGSYRPGNF
DMAFNGPIGASSALRLSLNVPSVDLLQRVGPARFAARLSHSGIQLRFPPGSTPNLSLILG
GTGARLEDLVGAFAALNRNGIAGRVRYTDDEPMIERRLASPGASWIVREMLESNPRPGYS
VGTFDVGGRPRVAWKTGTSYGYRDAWAIGSTRHYTVGVWVGRPDGTPLPGQYGAVTALPL
MFEVVDSLPRQRGDSAAAPMPASVSQEDICWPTGERAEGLPAALCQRLMPAYLLEGAAPP
TFPEREARRWQPGRQRYLADARTGLRVSADCRLPHEEVAREIARWPALLSPWLSKATREA
SQLPALSPDCRDDGREASVALHIDGLNDGATLARAPNSEHGVRLQLRALGSEQAVDWLLD
GRWIAQTRGAQLMQREFAEPGAHTLTALAADGAWTQVRFNVLR

Enzyme Prediction     

No EC number prediction in MGYG000002886_01428.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	1	86	3.6e-26	0.480225988700565

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK11240	PRK11240	0.0	3	641	141	771	penicillin-binding protein 1C; Provisional
TIGR02073	PBP_1c	0.0	1	641	111	726	penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG4953	PbpC	0.0	1	643	135	733	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
COG0744	MrcB	9.33e-84	1	420	155	588	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	1.01e-81	4	420	83	520	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
SNW12381.1	0.0	1	643	151	793
AIL08047.1	0.0	1	643	151	793
QNG71741.1	0.0	1	643	147	789
QGM10938.1	0.0	1	643	151	793
QGL68810.1	0.0	1	643	151	793

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3ZG8_B	3.32e-21	6	401	2	431	CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
4OON_A	4.07e-19	2	445	118	739	Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
3ZG7_B	7.04e-18	6	401	2	431	CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
3UDF_A	8.06e-18	4	420	120	707	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]
3DWK_A	2.56e-16	6	401	110	556	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P76577	4.08e-171	3	639	143	767	Penicillin-binding protein 1C OS=Escherichia coli (strain K12) OX=83333 GN=pbpC PE=1 SV=1
P38050	1.01e-31	4	401	148	569	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2
Q00573	4.01e-24	4	410	155	609	Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
P71707	1.30e-22	12	414	285	726	Penicillin-binding protein 1A OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=ponA1 PE=1 SV=3
Q04707	1.84e-21	4	417	154	615	Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000071	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002886_01428.