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CAZyme Information: MGYG000002827_02242
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phyllobacterium sp900539805 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales_A; Rhizobiaceae_A; Phyllobacterium; Phyllobacterium sp900539805 | |||||||||||
| CAZyme ID | MGYG000002827_02242 | |||||||||||
| CAZy Family | AA3 | |||||||||||
| CAZyme Description | Oxygen-dependent choline dehydrogenase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 43432; End: 45093 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| AA3 | 7 | 530 | 3e-159 | 0.9911971830985915 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR01810 | betA | 0.0 | 8 | 535 | 1 | 532 | choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli, Staphylococcus xylosus, and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified. [Cellular processes, Adaptations to atypical conditions] |
| PRK02106 | PRK02106 | 0.0 | 5 | 553 | 4 | 555 | choline dehydrogenase; Validated |
| COG2303 | BetA | 0.0 | 1 | 535 | 2 | 539 | Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]. |
| TIGR03970 | Rv0697 | 8.45e-101 | 7 | 530 | 1 | 487 | dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
| pfam00732 | GMC_oxred_N | 1.19e-62 | 75 | 297 | 15 | 218 | GMC oxidoreductase. This family of proteins bind FAD as a cofactor. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CAB3230510.1 | 1.66e-181 | 6 | 544 | 24 | 570 |
| ANI26486.1 | 1.40e-178 | 9 | 535 | 73 | 607 |
| AWP09430.1 | 2.09e-178 | 9 | 535 | 22 | 556 |
| CAG5086058.1 | 1.58e-151 | 8 | 539 | 16 | 573 |
| CAG5089487.1 | 3.06e-150 | 8 | 539 | 18 | 568 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3LJP_A | 2.45e-93 | 6 | 529 | 13 | 526 | ChainA, Choline oxidase [Arthrobacter globiformis],3LJP_B Chain B, Choline oxidase [Arthrobacter globiformis] |
| 2JBV_A | 9.58e-93 | 6 | 529 | 13 | 526 | Crystalstructure of choline oxidase reveals insights into the catalytic mechanism [Arthrobacter globiformis],2JBV_B Crystal structure of choline oxidase reveals insights into the catalytic mechanism [Arthrobacter globiformis],4MJW_A Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine [Arthrobacter globiformis],4MJW_B Crystal Structure of Choline Oxidase in Complex with the Reaction Product Glycine Betaine [Arthrobacter globiformis] |
| 3NNE_A | 9.58e-93 | 6 | 529 | 13 | 526 | Crystalstructure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_B Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_C Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_D Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_E Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_F Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_G Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis],3NNE_H Crystal structure of choline oxidase S101A mutant [Arthrobacter globiformis] |
| 6ZH7_A | 3.01e-88 | 4 | 542 | 5 | 573 | ChainA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis],6ZH7_B Chain B, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis] |
| 6YRU_AAA | 5.94e-88 | 8 | 542 | 9 | 573 | ChainAAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRV_AAA Chain AAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRX_AAA Chain AAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRZ_AAA Chain AAA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A9M9H8 | 0.0 | 5 | 553 | 1 | 549 | Oxygen-dependent choline dehydrogenase OS=Brucella canis (strain ATCC 23365 / NCTC 10854) OX=483179 GN=betA PE=3 SV=1 |
| Q8YFY2 | 0.0 | 5 | 553 | 1 | 549 | Oxygen-dependent choline dehydrogenase OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) OX=224914 GN=betA PE=3 SV=2 |
| A5VPA6 | 0.0 | 5 | 553 | 1 | 549 | Oxygen-dependent choline dehydrogenase OS=Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512) OX=444178 GN=betA PE=3 SV=1 |
| B0CKN4 | 0.0 | 5 | 553 | 1 | 549 | Oxygen-dependent choline dehydrogenase OS=Brucella suis (strain ATCC 23445 / NCTC 10510) OX=470137 GN=betA PE=3 SV=1 |
| Q985M5 | 0.0 | 5 | 553 | 2 | 550 | Oxygen-dependent choline dehydrogenase OS=Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) OX=266835 GN=betA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000031 | 0.000003 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |