CAZyme Information: MGYG000002717_01230

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides
• CAZyme ID: MGYG000002717_01230
• CAZy Family: GH88
• CAZyme Description: Unsaturated chondroitin disaccharide hydrolase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
396		45435.75	7.8278

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002717	5602088	MAG	Canada	North America

• Gene Location: Start: 1716; End: 2906 Strand: +

Full Sequence      

MENILLFCTILTGLLFAPNKQEEPLSGVIERGLNVSRQQTLLLAKEMEAKENRLPKTYEN
GVLQTANYKSWISGFFPGVLWYLYEDTPTEELKKYAELYTLRVMPAKDMTSTHDLGFMLY
CSFGNGYRLTGNKSYMDVMKVGAESLASRYNDKVGAIKSWNSNKKWQFPVIIDNMMNLEF
LSFMALNTGNNRFKEIADKHAKTTLSNHFRSDNSCYHVVSYDTITGIPHAKQTHQGYADN
SSWARGQAWALYGYTMMYRETNNKVYLEQARKVALFIKNHPNLPEDKVPYWDFDAPDIPK
AYRDASAAAIMASAFLELSSLDKSEDRIEWLKLGEQQIRSLSSPLYLAEPNTNGGFILKH
SVGNFNKKSEVDVPLTYADYYYVEALLRLKRMQNEK

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH88	65	389	1.5e-124	0.9908814589665653

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07470	Glyco_hydro_88	1.42e-09	52	279	7	220	Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QJR58403.1	4.35e-213	1	395	1	395
QJR71294.1	4.35e-213	1	395	1	395
AII67843.1	4.35e-213	1	395	1	395
QJR66954.1	4.35e-213	1	395	1	395
AND19526.1	4.35e-213	1	395	1	395

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3WIW_A	2.55e-112	60	394	62	393	Crystalstructure of unsaturated glucuronyl hydrolase specific for heparin [Pedobacter heparinus DSM 2366]
2ZZR_A	3.23e-45	55	388	53	388	Crystalstructure of unsaturated glucuronyl hydrolase from Streptcoccus agalactiae [Streptococcus agalactiae]
3ANJ_A	3.29e-45	55	388	54	389	Crystalstructure of unsaturated glucuronyl hydrolase from Streptcoccus agalactiae [Streptococcus agalactiae serogroup III]
3WUX_A	4.60e-45	55	388	54	389	Crystalstructure of unsaturated glucuronyl hydrolase mutant D115N/K370S from Streptococcus agalactiae [Streptococcus agalactiae NEM316]
3ANI_A	1.74e-44	55	388	54	389	Crystalstructure of unsaturated glucuronyl hydrolase mutant D175N from Streptcoccus agalactiae [Streptococcus agalactiae serogroup III],3ANK_A Crystal structure of unsaturated glucuronyl hydrolase mutant D175N from Streptcoccus agalactiae complexed with dGlcA-GalNAc6S [Streptococcus agalactiae serogroup III]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
T2KLZ3	5.16e-103	62	394	68	396	Unsaturated glucuronyl hydrolase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21900 PE=1 SV=1
Q8DR77	1.20e-45	55	394	52	393	Unsaturated chondroitin disaccharide hydrolase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=ugl PE=1 SV=1
Q8E372	1.80e-44	55	388	54	389	Unsaturated chondroitin disaccharide hydrolase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=gbs1889 PE=1 SV=1
Q9A0T3	3.59e-44	55	394	55	396	Unsaturated chondroitin disaccharide hydrolase OS=Streptococcus pyogenes serotype M1 OX=301447 GN=ugl PE=1 SV=1
Q9RC92	8.75e-43	42	391	12	366	Unsaturated glucuronyl hydrolase OS=Bacillus sp. (strain GL1) OX=84635 GN=ugl PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.004281	0.994391	0.000672	0.000216	0.000199	0.000210

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002717_01230.