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CAZyme Information: MGYG000002653_01914

You are here: Home > Sequence: MGYG000002653_01914

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella sp002251295
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp002251295
CAZyme ID MGYG000002653_01914
CAZy Family GH137
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1280 146013.19 7.5838
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002653 3045320 MAG United Republic of Tanzania Africa
Gene Location Start: 21333;  End: 25175  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.31 3.2.1.185

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH137 33 380 4.6e-149 0.9911764705882353
GH2 382 899 7.9e-75 0.5877659574468085
CBM57 971 1132 6.9e-42 0.9863945578231292

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam11721 Malectin 1.45e-32 969 1141 1 161
Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognizes and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan.
COG3250 LacZ 4.03e-28 442 780 90 407
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 9.66e-21 450 800 125 469
cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525 lacZ 5.60e-12 486 780 173 463
beta-galactosidase.
pfam00703 Glyco_hydro_2 1.51e-11 545 653 1 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCS84862.1 0.0 25 1280 12 1273
QNT66957.1 0.0 13 1280 10 1329
QUR43084.1 0.0 35 1280 23 1399
QRN01915.1 0.0 35 1280 23 1399
SCV09658.1 0.0 35 1280 23 1399

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MUI_A 1.24e-187 12 386 10 380
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482]
5MT2_A 5.97e-181 12 386 10 380
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482],5MUJ_A BT0996 RGII Chain B Complex [Bacteroides thetaiotaomicron VPI-5482]
6MVF_A 1.30e-29 373 898 12 531
Crystalstructure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 [Faecalibacterium prausnitzii L2-6],6MVF_B Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 [Faecalibacterium prausnitzii L2-6],6MVF_C Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 [Faecalibacterium prausnitzii L2-6],6MVF_D Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 [Faecalibacterium prausnitzii L2-6],6MVF_E Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 [Faecalibacterium prausnitzii L2-6],6MVF_F Crystal structure of FMN-binding beta-glucuronidase from Facaelibacterium prausnitzii L2-6 [Faecalibacterium prausnitzii L2-6]
3FN9_A 1.56e-28 389 812 5 433
Crystalstructure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343],3FN9_B Crystal structure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343],3FN9_C Crystal structure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343],3FN9_D Crystal structure of putative beta-galactosidase from bacteroides fragilis [Bacteroides fragilis NCTC 9343]
3GM8_A 6.93e-28 390 799 5 417
ChainA, Glycoside hydrolase family 2, candidate beta-glycosidase [Phocaeicola vulgatus ATCC 8482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
T2KM09 3.77e-26 392 800 49 451
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KPJ7 7.54e-25 413 923 82 615
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P06864 7.28e-18 450 780 125 450
Evolved beta-galactosidase subunit alpha OS=Escherichia coli (strain K12) OX=83333 GN=ebgA PE=1 SV=4
A1SWB8 2.17e-17 451 782 135 463
Beta-galactosidase OS=Psychromonas ingrahamii (strain 37) OX=357804 GN=lacZ PE=3 SV=1
P81650 9.78e-16 437 779 126 460
Beta-galactosidase OS=Pseudoalteromonas haloplanktis OX=228 GN=lacZ PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000283 0.999031 0.000156 0.000176 0.000160 0.000145

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002653_01914.