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CAZyme Information: MGYG000002506_04318
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Escherichia coli_D | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli_D | |||||||||||
| CAZyme ID | MGYG000002506_04318 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 4510382; End: 4511530 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 9 | 366 | 1e-141 | 0.9943502824858758 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR00215 | lpxB | 0.0 | 1 | 380 | 1 | 385 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| COG0763 | LpxB | 0.0 | 6 | 382 | 1 | 380 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| PRK00025 | lpxB | 0.0 | 6 | 382 | 1 | 376 | lipid-A-disaccharide synthase; Reviewed |
| pfam02684 | LpxB | 0.0 | 9 | 377 | 1 | 374 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| PRK01021 | lpxB | 6.02e-49 | 11 | 328 | 231 | 551 | lipid-A-disaccharide synthase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QJF85737.1 | 2.70e-278 | 1 | 382 | 1 | 382 |
| QFI51657.1 | 3.83e-278 | 1 | 382 | 1 | 382 |
| AWR80981.1 | 3.83e-278 | 1 | 382 | 1 | 382 |
| ACB17673.1 | 3.83e-278 | 1 | 382 | 1 | 382 |
| AXZ40372.1 | 1.56e-277 | 1 | 382 | 1 | 382 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8N_A | 1.96e-270 | 1 | 382 | 1 | 382 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
| 5W8S_A | 1.61e-269 | 1 | 382 | 1 | 382 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| B1LGY4 | 7.67e-279 | 1 | 382 | 1 | 382 | Lipid-A-disaccharide synthase OS=Escherichia coli (strain SMS-3-5 / SECEC) OX=439855 GN=lpxB PE=3 SV=1 |
| B7NIE4 | 3.12e-278 | 1 | 382 | 1 | 382 | Lipid-A-disaccharide synthase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) OX=585057 GN=lpxB PE=3 SV=1 |
| B1IQF9 | 4.43e-278 | 1 | 382 | 1 | 382 | Lipid-A-disaccharide synthase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) OX=481805 GN=lpxB PE=3 SV=1 |
| Q83SL3 | 1.27e-277 | 1 | 382 | 1 | 382 | Lipid-A-disaccharide synthase OS=Shigella flexneri OX=623 GN=lpxB PE=3 SV=2 |
| B7UJ83 | 2.56e-277 | 1 | 382 | 1 | 382 | Lipid-A-disaccharide synthase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) OX=574521 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000065 | 0.000010 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |