CAZyme Information: MGYG000002500_00118

Basic Information

• Species: Enterobacter cloacae
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Enterobacter; Enterobacter cloacae
• CAZyme ID: MGYG000002500_00118
• CAZy Family: GH23
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
151		17194.82	9.4333

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002500	5087499	Isolate	not provided	not provided

• Gene Location: Start: 119764; End: 120219 Strand: +

Full Sequence      

MKNVLLAGLLTITCPVIAQDCFEMAGRDYHIEPDLLRAISFRVSSWRPDAMNVISNESYA
VGMMQIHSQNFSHLAKYGITPGNLYRDPCMNIYTGAYYLAIAFKRWGYSWRAVGAYNAGF
RETDAQEKKRQQYAKEIQAIYLGIKKNAPPK

Enzyme Prediction     

No EC number prediction in MGYG000002500_00118.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH23	31	146	8.8e-18	0.8296296296296296

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK13722	PRK13722	8.33e-54	18	147	19	148	lytic transglycosylase; Provisional
cd13400	LT_IagB-like	1.36e-42	29	141	1	107	Escherichia coli invasion protein IagB and similar proteins. Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.
PRK15328	PRK15328	1.45e-29	1	145	1	143	type III secretion system invasion protein IagB.
pfam01464	SLT	1.92e-21	22	140	1	114	Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.
COG0741	MltE	6.09e-14	15	119	136	240	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASQ15781.1	4.21e-110	1	151	1	151
AWS99287.1	9.89e-100	1	150	1	150
QST30990.1	1.41e-99	1	150	1	150
QST40303.1	1.41e-99	1	150	1	150
AGR61870.1	1.16e-98	1	151	1	151

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4XP8_A	3.94e-12	20	104	2	87	Structureof EtgA D60N mutant [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P47737	8.14e-53	18	145	19	146	X polypeptide OS=Escherichia coli (strain K12) OX=83333 GN=yubQ PE=3 SV=1
Q00739	1.64e-52	18	145	19	146	X polypeptide OS=Escherichia coli OX=562 GN=X PE=3 SV=1
P17738	3.29e-52	18	145	19	146	X polypeptide OS=Escherichia coli OX=562 GN=X PE=3 SV=1
P14499	4.67e-52	18	145	19	146	X polypeptide OS=Escherichia coli OX=562 GN=X PE=3 SV=1
E1WAC2	4.61e-21	20	145	20	143	Invasion protein IagB OS=Salmonella typhimurium (strain SL1344) OX=216597 GN=iagB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000618	0.997916	0.000798	0.000216	0.000207	0.000204

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002500_00118.