CAZyme Information: MGYG000002478_01902

Basic Information

• Species: Phocaeicola dorei
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola dorei
• CAZyme ID: MGYG000002478_01902
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1122	MGYG000002478_1|CGC44	126803.92	5.9656

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002478	5444912	Isolate	Finland	Europe

• Gene Location: Start: 2476642; End: 2480010 Strand: +

Full Sequence      

MKKSIIAIAFLLLCPFYGVRAQERPFFDLSGKGWHLWQDKKATWQIEDIYLTLEEARKSP
VIVPTAGWDILTSAQAVPVQVPGTAEEYLQTQSGPEGDITGVTWWSRTMDIPVLKKGQKV
FLNFGSIRSRAEIFINQRLVDYQIVDNVPFETDITPYIKSGEQVQLAVRITDAGGNHDWR
DSRTIPWGDKMLPPGHGFGGITGKVGMKVCNAVYVADIYMQNTPQITTANAILTLQNEKG
KTTKQDLRITVYEWQNKEKIVYSKEIKGVSLNKGMNELKIPVSAPDAKLWSVDDPNLYVC
EVELSEGKNWVDKDSRRFGFRWFEASGIGEDAVFRLNGKRIMLRSAISWSFWPVNGIFPS
EELAERQIRIAKELGLNMLNFHRFIGNTDVMNYADELGLLYFEEPGGFRLDVKQPFMNAV
LHEKVIRMVKRDRSHPCLVIYNMMNESGNATPEKLELEIQAMKDMRVLDPSRLILRTSAW
AKGDDIEDQAKIHIRPYDEKVYWSGWYDYHRAGGPAVWNEGLYKGPEDYYNDTKNKREIV
FFGEEGALSSPPRLEKNKEDLEKYSYKGWDGREFLRWYDEFNEFLDAKQLRTVYPTVDDL
CVAMGTVSYEHQGRKIESARMNNLTDAYVVNGWESELTENYSGIVDCFRYPKSDPAIIAR
YNQPLYVAVKTRQQVAAAGGEVTVDFYLINEKNVRGNHQLKISVTDSQGKVMEVGTYETE
AAGGEVYGQLLVKDVKIPVPTAGGLCRIEAKLCKENSVVTTGYDDILSVNLASNMLDGKG
AVWEDGSALQNFLKGKTKEAVAAYEDNLGKLDWIMVARPPRKDQLTMVPMEALRSADGKP
GLDVVYYEDMEFQKEVYHEVAKVVNLSAIEGATPSPFVYMLDGYGIKWSGKVLPSVSGEY
TIIPQSNDRSMIEVFVNGKKIYEITRKKKHLGDGKVYLEGGKSADIEIRFRHPRSNARCR
LDWAVPNDKMPDAQRLMERAVNDGTKIFIIQSADEWSEFIAVNSKAVFKDKFFVGTNWLG
GVMFNKPHDIFKELPVGNALNWPYQALIHTGVERIGLVMEGEELLVGAYHTYPMAIGTAM
GIVPMGKGSVLFSTLDIYGNIINDSAAGLVAKKLIFNMIDFK

Enzyme Prediction     

No EC number prediction in MGYG000002478_01902.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	69	716	7.4e-71	0.6476063829787234

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	3.81e-31	23	589	9	563	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	4.75e-20	101	472	65	443	beta-D-glucuronidase; Provisional
pfam00703	Glyco_hydro_2	2.98e-16	213	321	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10340	ebgA	7.50e-15	107	474	115	472	cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525	lacZ	4.79e-12	149	448	169	464	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QJR56768.1	0.0	1	1122	1	1122
ALA73627.1	0.0	1	1122	1	1122
QJR58436.1	0.0	1	1122	1	1122
AII67878.1	0.0	1	1122	1	1122
QJR71326.1	0.0	1	1122	1	1122

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ED1_A	5.88e-27	101	507	77	485	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei],6ED1_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Phocaeicola dorei]
6B6L_A	3.93e-22	81	472	48	432	Thecrystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838],6B6L_B The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838]
7RSK_A	6.85e-22	81	472	48	432	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7RSK_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
6U7J_A	1.18e-20	98	539	72	532	UnculturedClostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_B Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_C Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_D Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.]
3GM8_A	1.72e-19	81	472	45	419	ChainA, Glycoside hydrolase family 2, candidate beta-glycosidase [Phocaeicola vulgatus ATCC 8482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P77989	1.25e-25	96	447	51	389	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
P26257	3.28e-18	120	447	73	390	Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1
Q56307	3.58e-18	100	468	111	464	Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2
T2KN75	1.31e-17	94	548	80	540	Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
Q32JB6	2.33e-17	95	449	116	465	Beta-galactosidase OS=Shigella dysenteriae serotype 1 (strain Sd197) OX=300267 GN=lacZ PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000223	0.999073	0.000207	0.000167	0.000155	0.000137

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002478_01902.