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CAZyme Information: MGYG000002455_00256
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides cellulosilyticus | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides cellulosilyticus | |||||||||||
| CAZyme ID | MGYG000002455_00256 | |||||||||||
| CAZy Family | PL6 | |||||||||||
| CAZyme Description | Chondroitinase-B | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 325190; End: 326584 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| PL6 | 39 | 378 | 3.1e-104 | 0.9538904899135446 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd14251 | PL-6 | 2.29e-155 | 37 | 399 | 11 | 364 | Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate. |
| pfam14592 | Chondroitinas_B | 2.04e-86 | 39 | 399 | 13 | 378 | Chondroitinase B. This family includes chondroitinases. These enzymes cleave the glycosaminoglycan dermatan sulfate. |
| pfam13229 | Beta_helix | 1.05e-05 | 224 | 317 | 32 | 123 | Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases. |
| pfam05048 | NosD | 0.005 | 158 | 306 | 49 | 174 | Periplasmic copper-binding protein (NosD). NosD is a periplasmic protein which is thought to insert copper into the exported reductase apoenzyme (NosZ). This region forms a parallel beta helix domain. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUT90411.1 | 0.0 | 1 | 464 | 1 | 464 |
| ALJ58476.1 | 0.0 | 1 | 464 | 1 | 464 |
| QDO71143.1 | 0.0 | 1 | 464 | 2 | 465 |
| QDO71096.1 | 4.66e-153 | 18 | 418 | 21 | 434 |
| AXP82110.1 | 1.06e-76 | 1 | 400 | 1 | 389 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6QPS_A | 0.0 | 16 | 464 | 19 | 467 | Structuralcharacterization of a mannuronic acid specific polysaccharide family 6 lyase enzyme from human gut microbiota [Bacteroides cellulosilyticus],6QPS_B Structural characterization of a mannuronic acid specific polysaccharide family 6 lyase enzyme from human gut microbiota [Bacteroides cellulosilyticus] |
| 5GKD_A | 4.98e-64 | 41 | 426 | 19 | 388 | Structureof PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_B Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_C Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_D Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis] |
| 5GKQ_A | 3.55e-63 | 41 | 426 | 19 | 388 | Structureof PL6 family alginate lyase AlyGC mutant-R241A [Paraglaciecola chathamensis S18K6],5GKQ_B Structure of PL6 family alginate lyase AlyGC mutant-R241A [Paraglaciecola chathamensis S18K6] |
| 7O84_A | 1.16e-60 | 35 | 452 | 27 | 423 | ChainA, Alginate lyase [Pseudopedobacter saltans DSM 12145],7O84_B Chain B, Alginate lyase [Pseudopedobacter saltans DSM 12145] |
| 7O7A_A | 1.19e-60 | 35 | 452 | 27 | 423 | ChainA, Aliginate lyase [Pseudopedobacter saltans DSM 12145],7O7A_B Chain B, Aliginate lyase [Pseudopedobacter saltans DSM 12145] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q06365 | 2.98e-55 | 42 | 451 | 2 | 390 | Alginate lyase OS=Pseudomonas sp. (strain OS-ALG-9) OX=86038 GN=aly PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000280 | 0.998963 | 0.000247 | 0.000157 | 0.000160 | 0.000150 |