CAZyme Information: MGYG000002438_03267

Basic Information

• Species: Parabacteroides distasonis
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae; Parabacteroides; Parabacteroides distasonis
• CAZyme ID: MGYG000002438_03267
• CAZy Family: GH127
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
623		70761.93	6.0101

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002438	5030699	Isolate	South Korea	Asia

• Gene Location: Start: 469475; End: 471346 Strand: +

Full Sequence      

MSISVLTKGMSCLFFCFCVCCMNAQVRNTDPVRHLRISGYLGQRIDACIEYRVKAQDVDH
LVEPFRHKEETLRWQSEFWGKWIQGAIASYRYDKDPELYKIIKNGAESLMETQLPNGYIG
NYSEEAQLNQWDIWGRKYTALGLIAYYDLSGDRKALDAACRVIDHLMTQVGPGKVNIVTT
GNYIGMPSSSVLEPVMYLYNRTRQDKYLDFAKYIVKQWETPEGPRLISKAIADIPVAGRF
PHPKVWFSPENGQKAYEMMSCYEGLLELYKVTKNPLYLSVVEKTMNHIINEEINVAGSGS
AFECWYGGKALQTYPTYHTMETCVTFTWMQICDRMLGLTGNSLYADQIEKAMYNALLASL
KADASQIAKYSPLEGWRHEGEEQCGMHINCCNANGPRAFAMIPQFAYQINGRRIDVNLYA
ASSVEVELDKKTRVSMTQETNYPIDGQVRIVVEPEKTSDFTIALRIPAWSERTVVSVNGE
PLTDLLAGAYLPIHRTWEKGDEITVELDMRARLVELNEAQAIVRGPLVLARDSRFKDGDV
DEASVIVSKDGYVELTPVQAPDFAWMAFTVPMVLGTDLEGNGKARPIHLCDFASAGNTWN
QAERYRVWLPKTWNVMRTPYKPY

Enzyme Prediction     

No EC number prediction in MGYG000002438_03267.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	67	529	1e-67	0.9122137404580153

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	1.07e-76	38	530	6	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	1.51e-67	24	530	6	501	Uncharacterized conserved protein, DUF1680 family [Function unknown].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ARE60508.1	4.65e-234	32	623	24	620
AXC10260.1	5.82e-50	81	531	133	592
QHS51661.1	5.85e-49	81	555	123	608
QOY86860.1	2.05e-48	81	538	97	557
QIA24125.1	9.80e-46	31	528	30	579

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4QJY_A	3.49e-40	27	554	25	582	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	1.09e-37	27	554	25	582	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
5MQO_A	5.95e-34	75	533	90	610	Glycosidehydrolase BT_1003 [Bacteroides thetaiotaomicron]
3WRE_A	1.54e-22	81	540	80	576	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	1.58e-22	81	540	80	576	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	8.43e-22	81	540	80	576	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.026171	0.972691	0.000532	0.000199	0.000187	0.000190

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002438_03267.