CAZyme Information: MGYG000002437_02476

Basic Information

• Species: Blautia hominis
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia; Blautia hominis
• CAZyme ID: MGYG000002437_02476
• CAZy Family: GH30
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1355	MGYG000002437_3|CGC6	148840.83	4.0339

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002437	5878941	Isolate	South Korea	Asia

• Gene Location: Start: 429537; End: 433604 Strand: +

Full Sequence      

MKKRRYRKTVAGISAFVMGAAAVIPSAVPVMADREADMRGNITVDPDIHYQTLEGWGTSL
CWWGNTIGSWGDADWNGDGRPDREEIAELAFSPEYLNLNVVRYNVGGGDKEDSSIKRCEG
LVPGWTEDMTGTADGTAPFQAEEFYAKSTEEMKDAGQLWMLEQANAYRKAYAEETGQEND
VINKVFSNSPPYYMTKSGTSTGGTGWDPNNLKDDCYDDFAMYLARATEWVDKNLESKYGA
GVSYVEPLNEPDTSYWYEGSTKQEGCIFNTGELQSKAYREMQYALNADEFQGSLDDVRIT
GTDETSLWNAINSFNRLDDDVKSNLETISAHTYSGSDSERRELRSIARKYDKGLWMSEVT
KGGGSHYDGCHESMEAGNTRSQSEGIMADLKELQSSAWIAWLVADSEYECLQTNSNWGLL
HAVFEKDGQPVPDYHTNLVDGNGSRLDWVPGEGYWAVTKQFYTMMQYSKYLKAGYTMIEI
DDSNMCAAISPQGDELVIVAQNFGDDRNDTVDLGAFPGAEEAELYRTSDSESCELAEVQD
VTDGVLDVTLPWNSVSTYVIKAADGSSICNPENYAEIVEADVEMPGESWVSDIDKFSYED
SWGESSEDFGGGKYSTAENASATLTFEGTQALIYGSKAPEGAVVNISVDGGDAEQVSLAA
DNKDGGSLLYNTGELSQGSHTVTITKAEGQGDRLLELNYAKVVRGTLDERIEKIEESGDL
YTVSGITPALPTKVYALTNMGNRIEKDVVWDLEGIDFTENTTLKGSVEGASVKAAANVKI
VPENVQYFIDCNSPDSPEYYRVDGYADLLNETADRKYTDGSWGRMEDYGAYDGDINDNYD
TGWYAGQGQAISYTVPLEKSTYRLNLGFKEWWNQDRPMKVSLNTGGETIELGKTNTWNSG
NPWNEETYEFTCDRAGNATITIAADGGPDPVLSYIRIQNILELQALKDAVNQAEEIDRDP
YQNEKLAVLDEAAAAGRSLLFRADAAQNDIDLAAEKIRLAIEDLNGGVQTEADMTSLNLA
ILMAEKMEAQQAENNCYTADSWKMAAEALAEARTVKENPEASQNAVDEVFLKLLTACNLL
EDGVQKTGLKAAMEGADTILGDEVVLEQYTSDSVEAVRAALKKAQQVYGSEAADQETVNQ
AARELMDAVTRLLAREEATRLDILIQKAEGLLEREEQYTPSSILKLKEALEAAKAASGSS
QADEGGLWQAYELLAEAMTSLVRKADKAELKNALDKAEEILSEAEKYLESSIAGLQRLTD
ETKVVYDDAEADKERVGNALKRLIDEILKARLMGDVDLNGAVDTEDTAAVLKYNAELAEF
TDEQQQAADVDRNGIADSSDAAVILQFAAEKIKSF

Enzyme Prediction     

No EC number prediction in MGYG000002437_02476.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH30	42	558	1.3e-122	0.9978070175438597

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam14587	Glyco_hydr_30_2	1.03e-21	42	402	4	354	O-Glycosyl hydrolase family 30.
cd14256	Dockerin_I	1.16e-09	1294	1347	2	55	Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
COG5520	XynC	1.38e-09	3	559	2	427	O-Glycosyl hydrolase [Cell wall/membrane/envelope biogenesis].
cd14255	Dockerin_III	7.84e-09	1294	1350	1	62	Type III dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. Two specific calcium-dependent interactions between cohesin and dockerin appear to be essential for cellulosome assembly, type I and type II. This subfamily represents the atypical type III dockerins and related domains.
cd14253	Dockerin	6.63e-06	1294	1349	1	56	Dockerin repeat domain. Dockerins are modules in the cellulosome complex that often anchor catalytic subunits by binding to cohesin domains of scaffolding proteins. Three types of dockerins and their corresponding cohesin have been described in the literature. This alignment models two consecutive dockerin repeats, the functional unit.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QIB57138.1	0.0	2	1355	3	1347
QMW80085.1	0.0	2	1355	3	1347
AWY99102.1	0.0	1	1355	1	1359
ADL05173.1	3.74e-284	6	1022	7	1275
ASU27677.1	2.53e-129	115	1011	302	1052

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3CLW_A	5.55e-15	44	565	10	501	Crystalstructure of conserved exported protein from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3CLW_B Crystal structure of conserved exported protein from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3CLW_C Crystal structure of conserved exported protein from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3CLW_D Crystal structure of conserved exported protein from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3CLW_E Crystal structure of conserved exported protein from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3CLW_F Crystal structure of conserved exported protein from Bacteroides fragilis [Bacteroides fragilis NCTC 9343]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A0A401ETL2	7.90e-35	14	566	14	613	Exo-beta-1,6-galactobiohydrolase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=bl1,6Gal PE=1 SV=1
Q76FP5	5.61e-25	23	513	5	420	Endo-beta-1,6-galactanase OS=Hypocrea rufa OX=5547 GN=6GAL PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.001772	0.996782	0.000315	0.000476	0.000342	0.000305

TMHMM  Annotations     

start	end
13	32