CAZyme Information: MGYG000002399_01980

Basic Information

• Species: Staphylococcus hominis
• Lineage: Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus hominis
• CAZyme ID: MGYG000002399_01980
• CAZy Family: GT51
• CAZyme Description: Monofunctional glycosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
270		31788.73	9.8035

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002399	2175331	Isolate	not provided	not provided

• Gene Location: Start: 88390; End: 89202 Strand: +

Full Sequence      

MKRRQRDNYPKEKTTYYQNEPYYNTYYQPVGSPPKKKKSKRLFLRMFIIFLIIFALFTGL
MYFLSSRANVDDLQTIENKSNFVSSDNMPNYVKGAFISMEDERFSKHHGFDIKGTTRALF
STIGEREVQGGSTITQQTVKNYYYNNERSFTRKLKELFVAHKVEQQYSKNQILSFYLNNI
YYGNDQYDIESAANYYFGTTTNQNNSSYPIITILQSAMLASKVNAPSVYDINNVSNNFKN
RIKVNLEKMRQQNYISDSQYQESLSQLNNY

Enzyme Prediction     

EC	2.4.1.129

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	77	249	1.8e-56	0.9378531073446328

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK13481	PRK13481	7.07e-136	41	267	6	232	glycosyltransferase; Provisional
pfam00912	Transgly	1.42e-67	77	250	10	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG0744	MrcB	6.38e-67	41	266	13	257	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
TIGR02074	PBP_1a_fam	1.13e-56	82	264	4	180	penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG5009	MrcA	3.73e-54	41	266	3	247	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QIY36669.1	3.25e-184	1	270	1	270
AVI06979.1	3.25e-184	1	270	1	270
QDW86556.1	3.25e-184	1	270	1	270
QGR80202.1	1.73e-179	1	270	1	270
QKH81731.1	1.42e-178	1	270	1	270

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5ZZK_A	1.20e-117	28	268	5	245	ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50]
3VMQ_A	5.84e-115	28	268	22	262	ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50],3VMQ_B Chain B, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50],3VMR_A Chain A, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50],3VMS_A Chain A, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50],3VMS_B Chain B, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50],3VMT_A Chain A, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50],3VMT_B Chain B, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus Mu50]
3HZS_A	3.42e-106	61	268	2	209	ChainA, Monofunctional glycosyltransferase [Staphylococcus aureus subsp. aureus MW2]
6FTB_A	3.54e-106	61	268	3	210	Staphylococcusaureus monofunctional glycosyltransferase in complex with moenomycin [Staphylococcus aureus MW2]
3UDF_A	1.10e-28	89	266	49	219	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q4L7I0	2.63e-152	1	270	1	270	Monofunctional glycosyltransferase OS=Staphylococcus haemolyticus (strain JCSC1435) OX=279808 GN=mgt PE=3 SV=1
Q5HN60	1.71e-122	16	269	16	269	Monofunctional glycosyltransferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=mgt PE=3 SV=1
Q8CNQ3	1.71e-122	16	269	16	269	Monofunctional glycosyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=mgt PE=3 SV=1
Q6GFI3	2.67e-119	1	268	1	268	Monofunctional glycosyltransferase OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=mgt PE=3 SV=1
Q6G860	2.67e-119	1	268	1	268	Monofunctional glycosyltransferase OS=Staphylococcus aureus (strain MSSA476) OX=282459 GN=mgt PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999947	0.000069	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
42	64