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CAZyme Information: MGYG000002359_02859
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Mycobacterium tuberculosis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis | |||||||||||
| CAZyme ID | MGYG000002359_02859 | |||||||||||
| CAZy Family | GT1 | |||||||||||
| CAZyme Description | 4'-demethylrebeccamycin synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 413367; End: 414533 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT1 | 6 | 387 | 3.3e-30 | 0.9397905759162304 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1819 | YjiC | 3.07e-69 | 1 | 357 | 2 | 369 | UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]. |
| cd03784 | GT1_Gtf-like | 7.21e-26 | 1 | 357 | 1 | 376 | UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. |
| cd03785 | GT28_MurG | 6.89e-09 | 285 | 357 | 247 | 325 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| pfam04101 | Glyco_tran_28_C | 7.11e-07 | 285 | 357 | 66 | 144 | Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. |
| COG0707 | MurG | 1.95e-06 | 285 | 357 | 247 | 325 | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAH27028.1 | 1.88e-272 | 1 | 388 | 1 | 388 |
| AMC91161.1 | 1.88e-272 | 1 | 388 | 1 | 388 |
| AHJ55978.1 | 1.88e-272 | 1 | 388 | 1 | 388 |
| AGL32227.1 | 1.88e-272 | 1 | 388 | 1 | 388 |
| AMC78553.1 | 1.88e-272 | 1 | 388 | 1 | 388 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A5U6W6 | 4.92e-07 | 290 | 367 | 327 | 406 | PGL/p-HBAD biosynthesis glycosyltransferase MRA_2985 OS=Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) OX=419947 GN=MRA_2985 PE=3 SV=1 |
| P9WFR0 | 4.92e-07 | 290 | 367 | 327 | 406 | PGL/p-HBAD biosynthesis glycosyltransferase MT3034 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT3034 PE=3 SV=1 |
| P9WFR1 | 4.92e-07 | 290 | 367 | 327 | 406 | PGL/p-HBAD biosynthesis glycosyltransferase Rv2958c OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2958c PE=1 SV=1 |
| Q751Z4 | 7.07e-06 | 287 | 365 | 1094 | 1172 | Sterol 3-beta-glucosyltransferase OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=ATG26 PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999948 | 0.000107 | 0.000001 | 0.000000 | 0.000000 | 0.000000 |